ASF1B

This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. [provided by RefSeq, Jul 2008]
Full Name
Anti-Silencing Function 1B Histone Chaperone
Function
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis.
Biological Process
Blastocyst hatching Source: Ensembl
Cell differentiation Source: UniProtKB-KW
DNA replication-dependent nucleosome assembly Source: UniProtKB
DNA replication-independent nucleosome assembly Source: UniProtKB
Spermatogenesis Source: UniProtKB-KW
Cellular Location
Nucleus
PTM
Phosphorylated by TLK1 and TLK2.
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Anti-ASF1B antibodies

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Human Recombinant ASF1B protein, His Tag (V2LY-0526-LY2180)

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Target: ASF1B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-202
Tag: His Tag
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (CBT3032) (V2LY-0625-LY715)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3032
Application*: WB
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (CBT2995) (V2LY-0625-LY714)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Monkey
Clone: CBT2995
Application*: WB, F
Datasheet SDS

Rabbit Anti-ASF1B Recombinant Antibody (EG272) (CBMAB-EN300-LY)

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Target: ASF1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: EG272
Application*: WB, IP
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (CBYC-A818) (CBMAB-A3760-YC)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYC-A818
Application*: E, WB, IF
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (CBYC-A817) (CBMAB-A3759-YC)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYC-A817
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (AT1D4) (CBMAB-A3758-YC)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: AT1D4
Application*: E, WB
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (4D5-2C2) (CBMAB-A3757-YC)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4D5-2C2
Application*: E, WB
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (1D4) (CBMAB-A3756-YC)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D4
Application*: WB, E
Datasheet SDS

Mouse Anti-ASF1B Recombinant Antibody (15B4) (CBMAB-A3755-YC)

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Target: ASF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 15B4
Application*: E, WB, FC
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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