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Mouse Anti-BGLAP Recombinant Antibody (2D5) (CBMAB-A0755-LY)

The product is antibody recognizes BGLAP. The antibody 2D5 immunoassay techniques such as: WB, ELISA.
See all BGLAP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2D5
Antibody Isotype
IgG1, λ
Application
WB, ELISA

Basic Information

Immunogen
BGLAP (NP_954642, 52 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, λ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Bone Gamma-Carboxyglutamate Protein
Entrez Gene ID
632
UniProt ID
P02818
Alternative Names
BGP; OC; PMF1
Function
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
Biological Process
Bone development Source: GO_Central
Bone mineralization Source: UniProtKB
Cell adhesion Source: UniProtKB
Cell aging Source: Ensembl
Cellular response to growth factor stimulus Source: Ensembl
Cellular response to vitamin D Source: Ensembl
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Odontogenesis Source: Ensembl
Osteoblast development Source: Ensembl
Osteoblast differentiation Source: BHF-UCL
Regulation of bone mineralization Source: InterPro
Regulation of bone resorption Source: UniProtKB
Regulation of cellular response to insulin stimulus Source: InterPro
Regulation of osteoclast differentiation Source: UniProtKB
Response to activity Source: Ensembl
Response to drug Source: Ensembl
Response to estrogen Source: Ensembl
Response to ethanol Source: Ensembl
Response to glucocorticoid Source: Ensembl
Response to gravity Source: Ensembl
Response to hydroxyisoflavone Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to testosterone Source: Ensembl
Response to vitamin D Source: BHF-UCL
Response to vitamin K Source: Ensembl
Response to zinc ion Source: Ensembl
Skeletal system development Source: ProtInc
Cellular Location
Secreted
PTM
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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