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Mouse Anti-CASP7 Recombinant Antibody (CBYY-C0982) (CBMAB-C2419-YY)

This product is mouse antibody that recognizes CASP7. The antibody CBYY-C0982 can be used for immunoassay techniques such as: WB, IP
See all CASP7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C0982
Antibody Isotype
IgG1, κ
Application
WB, IP

Basic Information

Immunogen
Human Caspase-7
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Caspase 7
Entrez Gene ID
840
UniProt ID
P55210
Alternative Names
Ciliogenesis Associated TTC17 Interacting Protein; C2orf62; Ciliogenesis-Associated TTC17-Interacting Protein; Chromosome 2 Open Reading Frame 62;
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
Biological Process
Apoptotic process Source: UniProtKB
Cellular response to staurosporine Source: CAFA
Execution phase of apoptosis Source: GO_Central
Proteolysis Source: UniProtKB
Cellular Location
Cytoplasm
PTM
Cleavages by granzyme B or caspase-10 generate the two active subunits. Propeptide domains can also be cleaved efficiently by caspase-3. Active heterodimers between the small subunit of caspase-7 and the large subunit of caspase-3, and vice versa, also occur.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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