Human CASP7 ELISA Kit (V2LY-0626-LY2663)

See all CASP7 antibodies
Go to compare Compare Online Inquiry
Tested Data
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.016 ng/mL
Detection Range
0.03-9 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
34.3 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Caspase 7
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
Biological Process
Apoptotic process Source: UniProtKB
Cellular response to staurosporine Source: CAFA
Execution phase of apoptosis Source: GO_Central
Proteolysis Source: UniProtKB
Cellular Location
Cytoplasm
PTM
Cleavages by granzyme B or caspase-10 generate the two active subunits. Propeptide domains can also be cleaved efficiently by caspase-3. Active heterodimers between the small subunit of caspase-7 and the large subunit of caspase-3, and vice versa, also occur.

Mahib, M. R., Hosojima, S., Kushiyama, H., Kinoshita, T., Shiroishi, T., Suda, T., & Tsuchiya, K. (2020). Caspase‐7 mediates caspase‐1‐induced apoptosis independently of Bid. Microbiology and immunology, 64(2), 143-152.

Safdar, M., Zaheer, S., Khailany, R. A., Parvez, S., Naveed, M., Bhuiyan, P., ... & Junejo, Y. (2020). The Relevance of SNPs at 3′ UTR Region of CASP7 and miR-371b-5p Associated Diseases: A Computational Analysis. Cell Biochemistry and Biophysics, 78(4), 541-557.

Gonçalves, A. V., Margolis, S. R., Quirino, G. F., Mascarenhas, D. P., Rauch, I., Nichols, R. D., ... & Zamboni, D. S. (2019). Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila. PLoS pathogens, 15(6), e1007886.

Pham, B., Eron, S. J., Hill, M. E., Li, X., Fahie, M. A., Hardy, J. A., & Chen, M. (2019). A nanopore approach for analysis of caspase-7 activity in cell lysates. Biophysical journal, 117(5), 844-855.

Shigemura, M., Lecuona, E., Angulo, M., Homma, T., Rodríguez, D. A., Gonzalez-Gonzalez, F. J., ... & Sznajder, J. I. (2018). Hypercapnia increases airway smooth muscle contractility via caspase-7–mediated miR-133a–RhoA signaling. Science translational medicine, 10(457).

Venkatesh, A., Cheng, S. Y., & Punzo, C. (2017). Loss of the cone-enriched caspase-7 does not affect secondary cone death in retinitis pigmentosa. Molecular vision, 23, 944.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Human CASP7 ELISA Kit?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Casp7 ELISA Kit (CAT#: V2LY-0626-LY1166)

Human Recombinant CASP7 protein, His Tag (CAT#: V2LY-0526-LY2600)

Related Products

Human Recombinant CASP7 protein, His Tag (CAT#: V2LY-0526-LY2600)

Mouse Anti-CASP7 Recombinant Antibody (CBFYC-0481) (CAT#: CBMAB-C0529-FY)

Mouse Anti-CASP7 Recombinant Antibody (CBYY-C0981) (CAT#: CBMAB-C2418-YY)

Mouse Casp7 ELISA Kit (CAT#: V2LY-0626-LY1166)

Rabbit Anti-CASP7 Recombinant Antibody (C2885) (CAT#: CBMAB-C2885-LY)

Mouse Anti-CASP7 Recombinant Antibody (CBT2044) (CAT#: V2LY-0625-LY179)

Rabbit Anti-CASP7 Recombinant Antibody (CBFYC-0851) (CAT#: CBMAB-C0906-FY)

Mouse Anti-CASP7 Recombinant Antibody (CBYY-C0982) (CAT#: CBMAB-C2419-YY)

Mouse Anti-CASP7 Recombinant Antibody (10-01-62) (CAT#: CBMAB-C2005-LY)

Mouse Anti-CASP7 Recombinant Antibody (CBFYC-0849) (CAT#: CBMAB-C0904-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.