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Rabbit Anti-DHX8 Recombinant Antibody (EG962) (CBMAB-EN1141-LY)

The product is antibody recognizes DHX8. The antibody EG962 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:5000.
See all DHX8 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
EG962
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:5000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human DHX8.
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
DEAH-Box Helicase 8
Introduction
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Entrez Gene ID
Human1659
Mouse217207
UniProt ID
HumanQ14562
MouseA2A4P0
Alternative Names
DEAH-Box Helicase 8; DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 8 (RNA Helicase); DEAH (Asp-Glu-Ala-His) Box Polypeptide 8; DEAH Box Protein 8; RNA Helicase HRH1; DDX8; ATP-Dependent RNA Helicase DHX8;
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346).

Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (PubMed:8608946).
Biological Process
mRNA splicing, via spliceosome Source: UniProtKB
RNA processing Source: ProtInc
RNA splicing Source: ProtInc
Spliceosomal complex disassembly Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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