DHX8

This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Full Name
DEAH-Box Helicase 8
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346).

Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (PubMed:8608946).
Biological Process
mRNA splicing, via spliceosome Source: UniProtKB
RNA processing Source: ProtInc
RNA splicing Source: ProtInc
Spliceosomal complex disassembly Source: GO_Central
Cellular Location
Nucleus
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Anti-DHX8 antibodies

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Mouse Anti-DHX8 Recombinant Antibody (1D6) (CBMAB-A2221-LY)

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Target: DHX8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D6
Application*: WB, E
Datasheet SDS

Mouse Anti-DHX8 Recombinant Antibody (EG962) (V2LY-0425-LY299)

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Target: DHX8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: EG962
Application*: WB, E, IP
Datasheet SDS

Mouse Anti-DHX8 Recombinant Antibody (A2221) (V2LY-0425-LY298)

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Target: DHX8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: A2221
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-DHX8 Recombinant Antibody (1E10) (V2LY-0425-LY297)

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Target: DHX8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 1E10
Application*: E, WB
Datasheet SDS

Rabbit Anti-DHX8 Recombinant Antibody (EG962) (CBMAB-EN1141-LY)

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Target: DHX8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: EG962
Application*: WB: 1:500~1:1000 ELISA: 1:5000
Datasheet SDS

Mouse Anti-DHX8 Recombinant Antibody (1E10) (CBMAB-D0862-YC)

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Target: DHX8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E10
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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