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Mouse Anti-LHB Recombinant Antibody (CBYJL-2525) (CBMAB-L2931-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Luteinizing Hormone Beta Polypeptide (LHB). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all LHB antibodies

Summary

Host Animal
Mouse
Specificity
Horse
Clone
CBYJL-2525
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Horse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
LHB
Introduction
Luteinizing hormone beta polypeptide promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Entrez Gene ID
100054774
UniProt ID
P08751
Alternative Names
LH/CG-beta; lutropin/choriogonadotropin subunit beta; LSH-B/CG-B; luteinizing hormone subunit beta; luteinizing hormone/chorionic gonadotrophin beta-subunit; lutropin/choriogonadotropin beta chain
Function
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Biological Process
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Male gonad developmentManual Assertion Based On ExperimentTAS:ProtInc
Progesterone biosynthetic processManual Assertion Based On ExperimentTAS:BHF-UCL
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
Involvement in disease
Hypogonadotropic hypogonadism 23 without anosmia (HH23):
A form of hypogonadotropic hypogonadism, a group of disorders characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. HH23 male patients have normal sexual differentiation, reduced or absent Leydig cells, reduced or absent spermatogenesis, and absence of spontaneous puberty. Female patients exhibit normal pubertal development and menarche, followed by oligomenorrhea and anovulatory secondary amenorrhea.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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