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Human Anti-LILRB4 Recombinant Antibody (CBXC-0716) (CBMAB-C1830-CQ)

This product is a recombinant human antibody that recognizes LILRB4. The antibody CBXC-0716 can be used for immunoassay techniques such as: FC.
Host Animal
Human
Application
FC
Antibody Isotype
IgG1
Cross Reactivity
Human
Clone
CBXC-0716
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Name
CD85K; ILT-3; ILT3; LIR-5; LIR5
Entrez Gene ID
UniProt ID
Cat CBMAB-C1830-CQ
Conjugates
Size
Price $
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