Mouse Anti-POSTN Recombinant Antibody (Stiny-1) (CBMAB-P2422-YC)

Name: Mouse Anti-POSTN Recombinant Antibody (Stiny-1)
SKU: CBMAB-P2422-YC
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

Stiny-1

Application

ELISA, IHC, WB

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid in PBS, 0.02% sodium azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Periostin

Introduction

POSTN is a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects.

Entrez Gene ID

10631

UniProt ID

Q15063

Alternative Names

OSF-2; OSF2; PDLPOSTN; PN

Function

Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007).
Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).

Biological Process

Cell adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular response to vitamin KManual Assertion Based On ExperimentIDA:UniProtKB
Extracellular matrix organizationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of Notch signaling pathwayIEA:Ensembl
Tissue developmentIEA:Ensembl

Cellular Location

Golgi apparatus
Secreted
Secreted, extracellular space, extracellular matrix
Colocalizes with BMP1 in the Golgi.

PTM

Gamma-carboxylation is controversial. Gamma-carboxyglutamated; gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation; this may be required for calcium binding (PubMed:18450759).
According to a more recent report, does not contain vitamin K-dependent gamma-carboxyglutamate residues (PubMed:26273833).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Postn ELISA Kit (CAT#: V2LY-0626-LY2854)

Mouse Recombinant POSTN protein, His Tag (CAT#: V2LY-0526-LY8767)

Human Recombinant POSTN protein, His Tag (CAT#: V2LY-0526-LY6110)

Rabbit Anti-POSTN Recombinant Antibody (
14F2) (CAT#: V2LY-0725-LY944)

Mouse Anti-POSTN Recombinant Antibody (47) (CAT#: CBMAB-P2418-YC)

Mouse Anti-POSTN (AA 1-230) Recombinant Antibody (CBXO-0536) (CAT#: CBMAB-O0643-CQ)

Human POSTN ELISA Kit (CAT#: V2LY-0626-LY3702)

Human Recombinant POSTN protein (CAT#: V2LY-0526-LY6111)

Mouse Anti-POSTN Recombinant Antibody (F-10) (CAT#: CBMAB-P2421-YC)

Rat Anti-POSTN Recombinant Antibody (8H152) (CAT#: CBMAB-P2419-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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