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Mouse Anti-SERPINA12 Recombinant Antibody (3B3) (CBMAB-A7989-LY)

The product is antibody recognizes SERPINA12. The antibody 3B3 immunoassay techniques such as: WB, ELISA.
See all SERPINA12 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3B3
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SERPINA12 (AAH40857, 1 a.a. ~ 414 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Serpin Family A Member 12
Entrez Gene ID
145264
UniProt ID
Q8IW75
Alternative Names
OL-64
Function
Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.
Biological Process
Biological Process gluconeogenesisIEA:Ensembl
Biological Process lipid biosynthetic processIEA:Ensembl
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of gluconeogenesisIEA:Ensembl
Biological Process negative regulation of lipid biosynthetic processIEA:Ensembl
Biological Process phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process positive regulation of insulin receptor signaling pathwayIEA:Ensembl
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process regulation of cholesterol metabolic processIEA:Ensembl
Biological Process regulation of triglyceride metabolic processIEA:Ensembl
Cellular Location
Secreted
PTM
Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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