Mouse Anti-SERPINA12 Recombinant Antibody (CBXS-3021) (CBMAB-S5767-CQ)

Name: Mouse Anti-SERPINA12 Recombinant Antibody (CBXS-3021)
SKU: CBMAB-S5767-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-3021

Application

ELISA, IP, WB

Immunogen

Full length recombinant protein corresponding to aa1-415 from human SERPINA12 (AAH40857) with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Serpin Family A Member 12

Introduction

SERPINA12 (Serpin Family A Member 12) is a Protein Coding gene. Diseases associated with SERPINA12 include Body Mass Index Quantitative Trait Locus 11 and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINA1.

Entrez Gene ID

145264

UniProt ID

Q8IW75

Alternative Names

Serpin Family A Member 12; Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Visceral Adipose Tissue-Derived Serine Protease Inhibitor; Vaspin; OL-64; Visceral Adipose-Specific SERPIN; Visceral Adipose-Specific Serpin; Serpin A12;

Function

Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.

Biological Process

Biological Process gluconeogenesisIEA:Ensembl
Biological Process lipid biosynthetic processIEA:Ensembl
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of gluconeogenesisIEA:Ensembl
Biological Process negative regulation of lipid biosynthetic processIEA:Ensembl
Biological Process phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process positive regulation of insulin receptor signaling pathwayIEA:Ensembl
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process regulation of cholesterol metabolic processIEA:Ensembl
Biological Process regulation of triglyceride metabolic processIEA:Ensembl

Cellular Location

Secreted

PTM

Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

SERPINA12 Matched Antibody Pair (1056) (CAT#: APMAB-1056LY)

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Mouse Anti-SERPINA12 (AA 21-414) Recombinant Antibody (CBXS-0224) (CAT#: CBMAB-S3205-CQ)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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