Sign in or Register   Sign in or Register
  |  

Mouse Anti-SH3KBP1 Recombinant Antibody (1F11) (CBMAB-A8100-LY)

The product is antibody recognizes SH3KBP1. The antibody 1F11 immunoassay techniques such as: WB, ELISA.
See all SH3KBP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F11
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SH3KBP1 (NP_114098.1, 224 a.a. ~ 308 a.a) partial recombinant protein with GST-pstS1 tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SH3 Domain Containing Kinase Binding Protein 1
Introduction
CBL (MIM 165360) constitutively interacts with SH3 domain-containing proteins and, upon tyrosine phosphorylation, with SH2 domain-containing proteins. The SH3KBP1 gene encodes an 85-kD CBL-interacting protein that enhances tumor necrosis factor (MIM 191160)-mediated apoptotic cell death (Narita et al., 2001 [PubMed 11474197]).[supplied by OMIM
Entrez Gene ID
30011
UniProt ID
Q96B97
Alternative Names
CIN85; GIG10; MIG18
Function
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
Biological Process
Biological Process positive regulation of epidermal growth factor receptor signaling pathwayISS:UniProtKB
Biological Process protein homooligomerizationIEA:InterPro
Cellular Location
Lysosome
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SH3KBP1 Recombinant Antibody (1F11)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare