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Mouse Anti-SH3KBP1 Recombinant Antibody (CBYY-C0726) (CBMAB-C2149-YY)

This product is mouse antibody that recognizes SH3KBP1. The antibody CBYY-C0726 can be used for immunoassay techniques such as: WB
See all SH3KBP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C0726
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
E. coli-derived recombinant human CIN85/SH3KBP1, Pro366-Lys665, Accession # Q96B97
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A/G purified
Preservative
PBS
Concentration
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SH3 Domain Containing Kinase Binding Protein 1
Entrez Gene ID
30011
UniProt ID
Q96B97
Alternative Names
Aldehyde Dehydrogenase 1 Family Member A1; Retinaldehyde Dehydrogenase 1; EC 1.2.1.36; RALDH 1; ALDH-E1; RALDH1; ALHDII; ALDH1; PUMB1; ALDC; Epididymis Secretory Sperm Binding Protein Li 53e; Aldehyde Dehydrogenase 1 Family, Member A1; Aldehyde Dehydrogenase Family 1 Member A1; Aldehyde Dehydrogenase, Liver Cytosolic;
Function
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
Biological Process
Biological Process positive regulation of epidermal growth factor receptor signaling pathwayISS:UniProtKB
Biological Process protein homooligomerizationIEA:InterPro
Cellular Location
Lysosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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