Mouse Anti-SH3KBP1 Recombinant Antibody (CBYY-C0726) (CBMAB-C2149-YY)

Name: Mouse Anti-SH3KBP1 Recombinant Antibody (CBYY-C0726)
SKU: CBMAB-C2149-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYY-C0726

Application

Immunogen

E. coli-derived recombinant human CIN85/SH3KBP1, Pro366-Lys665, Accession # Q96B97

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Protein A/G purified

Preservative

PBS

Concentration

Lyophilized

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SH3 Domain Containing Kinase Binding Protein 1

Entrez Gene ID

30011

UniProt ID

Q96B97

Alternative Names

Aldehyde Dehydrogenase 1 Family Member A1; Retinaldehyde Dehydrogenase 1; EC 1.2.1.36; RALDH 1; ALDH-E1; RALDH1; ALHDII; ALDH1; PUMB1; ALDC; Epididymis Secretory Sperm Binding Protein Li 53e; Aldehyde Dehydrogenase 1 Family, Member A1; Aldehyde Dehydrogenase Family 1 Member A1; Aldehyde Dehydrogenase, Liver Cytosolic;

Function

Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.

Biological Process

Biological Process positive regulation of epidermal growth factor receptor signaling pathwayISS:UniProtKB
Biological Process protein homooligomerizationIEA:InterPro

Cellular Location

Lysosome

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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