Sign in or Register   Sign in or Register
  |  

Rat Anti-Tigit Recombinant Antibody (CBYJT-3145) (CBMAB-T2416-YJ)

Provided herein is a Rat monoclonal antibody, which binds to Tigit (T cell immunoreceptor with Ig and ITIM domains). The antibody can be used for immunoassay techniques, such as FC.
See all Tigit antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJT-3145
Antibody Isotype
IgG2a, κ
Application
FC

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, 0.1% Gelatin
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
T cell immunoreceptor with Ig and ITIM domains
Introduction
Tigit functions in negative regulation of interleukin-12 production, negative regulation of T cell activation, positive regulation of interleukin-10 production.
Entrez Gene ID
100043314
UniProt ID
A0A0B4J1G6
Alternative Names
Vstm3
Function
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Biological Process
Biological Process negative regulation of interleukin-12 productionSource:UniProtKB1 Publication
Biological Process negative regulation of T cell activationSource:MGI1 Publication
Biological Process positive regulation of interleukin-10 productionSource:UniProtKB1 Publication
Cellular Location
Cell membrane
Topology
Extracellular: 22-141
Helical: 142-162
Cytoplasmic: 163-244
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rat Anti-Tigit Recombinant Antibody (CBYJT-3145)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare