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Mouse Anti-TNFRSF12A Recombinant Antibody (1B6) (CBMAB-A9264-LY)

The product is antibody recognizes TNFRSF12A. The antibody 1B6 immunoassay techniques such as: sELISA, ELISA.
See all TNFRSF12A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B6
Antibody Isotype
IgG2a, κ
Application
sELISA, ELISA

Basic Information

Immunogen
TNFRSF12A (AAH02718, 28 a.a. ~ 129 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
tumor necrosis factor receptor superfamily, member 12A
Entrez Gene ID
51330
UniProt ID
Q9NP84
Alternative Names
CD266; FN14; TWEAKR
Function
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Extracellular: 28-80
Helical: 81-101
Cytoplasmic: 102-129
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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