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Rabbit Anti-TNFRSF12A Recombinant Antibody (SP134) (CBMAB-F2692-CQ)

This product is a rabbit antibody that recognizes TNFRSF12A. The antibody SP134 can be used for immunoassay techniques such as: IHC-P, WB, FC.
See all TNFRSF12A antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
SP134
Antibody Isotype
IgG
Application
IHC-P, WB, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 1% BSA, pH 7.6
Preservative
0.1% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
tumor necrosis factor receptor superfamily, member 12A
Introduction
TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling.
Entrez Gene ID
51330
UniProt ID
Q9NP84
Alternative Names
TNF Receptor Superfamily Member 12A; Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14; FGF-Inducible 14; Tweak-Receptor; TWEAKR; FN14;
Function
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Extracellular: 28-80
Helical: 81-101
Cytoplasmic: 102-129
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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