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Mouse Anti-TNFRSF12A Recombinant Antibody (CBYJT-3708) (CBMAB-T3088-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TNFRSF12A (TNF Receptor Superfamily Member 12A). The antibody can be used for immunoassay techniques, such as FC, IHC-Fr, WB.
See all TNFRSF12A antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYJT-3708
Antibody Isotype
IgG2b
Application
FC, IHC-Fr, WB

Basic Information

Immunogen
Human CD266 transfected P815 cells
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
tumor necrosis factor receptor superfamily, member 12A
Introduction
TNF Receptor Superfamily Member 12A is a Protein Coding gene. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling.
Entrez Gene ID
Human51330
Mouse27279
Rat302965
UniProt ID
HumanQ9NP84
MouseQ9CR75
RatG3V6F9
Alternative Names
TNF Receptor Superfamily Member 12A; Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14; FGF-Inducible 14; Tweak-Receptor; TWEAKR; FN14
Function
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Extracellular: 28-80
Helical: 81-101
Cytoplasmic: 102-129
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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