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Mouse Anti-TNFRSF12A Recombinant Antibody (CBT4239) (V2LY-0625-LY1033)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4239
Antibody Isotype
IgG2a
Application
FC

Basic Information

Immunogen
Purified recombinant fragment of human TNFRSF12A (AA: extra 28-80) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
tumor necrosis factor receptor superfamily, member 12A
Entrez Gene ID
51330
Function
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Extracellular: 28-80
Helical: 81-101
Cytoplasmic: 102-129
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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