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Rat Anti-TNFRSF12A Recombinant Antibody (CBYJT-3705) (CBMAB-T3083-YJ)

Provided herein is a Rat monoclonal antibody, which binds to TNFRSF12A (TNF Receptor Superfamily Member 12A). The antibody can be used for immunoassay techniques, such as WB.
See all TNFRSF12A antibodies

Summary

Host Animal
Rat
Specificity
Human
Clone
CBYJT-3705
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
E. coli-derived recombinant human TWEAK R/TNFRSF12, Glu28-Trp79, Accession # Q9NP84.1
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 28-79

Target

Full Name
tumor necrosis factor receptor superfamily, member 12A
Introduction
TNF Receptor Superfamily Member 12A is a Protein Coding gene. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling.
Entrez Gene ID
51330
UniProt ID
Q9NP84
Alternative Names
TNF Receptor Superfamily Member 12A; Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14; FGF-Inducible 14; Tweak-Receptor; TWEAKR; FN14
Function
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Extracellular: 28-80
Helical: 81-101
Cytoplasmic: 102-129
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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