TNFRSF12A
TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling.
Full Name
tumor necrosis factor receptor superfamily, member 12A
Function
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cell adhesion Source:UniProtKB-KW
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of wound healing Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Extracellular: 28-80
Helical: 81-101
Cytoplasmic: 102-129
Helical: 81-101
Cytoplasmic: 102-129
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Anti-TNFRSF12A antibodies
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CompareTarget: TNFRSF12A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B6
Application*: SE, E
Target: TNFRSF12A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C1997
Application*: F, WB
Target: Tnfrsf12a
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJT-3712
Application*: WB, F, MC
Target: Tnfrsf12a
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJT-3711
Application*: WB
Target: Tnfrsf12a
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-3710
Application*: F, WB
Target: TNFRSF12A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBYJT-3708
Application*: F, C, WB
Target: TNFRSF12A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse
Clone: ITEM-4
Application*: WB, F, IH, C
Target: TNFRSF12A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3706
Application*: F, P, WB
Target: TNFRSF12A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-3705
Application*: WB
Target: TNFRSF12A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-3704
Application*: E
Target: TNFRSF12A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 314636
Application*: C, WB
Target: TNFRSF12A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP134
Application*: P, WB, F
Target: TNFRSF12A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Human
Clone: ITEM-1
Application*: E, FN
Target: TNFRSF12A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Mouse, Human
Clone: CBXF-2430
Application*: E, FN
Target: TNFRSF12A
Sensitivity: 0.027 ng/mL
Detection Range: 0.05-30 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: TNFRSF12A
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 28-79
Tag: hFc Tag
Target: TNFRSF12A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 7H8
Application*: E, WB, IH
Target: TNFRSF12A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT4239
Application*: F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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