FCN1 Matched Antibody Pair (420) (APMAB-420LY)

Name: FCN1 Matched Antibody Pair (420)
SKU: APMAB-420LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-FCN1 polyclonal antibody, 100 ug

Detection Antibody

Anti-FCN1 Mouse monoclonal, IgG2a antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]

Alternative Names

Ficolin 1; Ficolin (Collagen/Fibrinogen Domain-Containing) 1; Ficolin-Alpha; Ficolin-A; M-Ficolin; FCNM; Ficolin (Collagen/Fibrinogen Domain Containing) 1; Collagen/Fibrinogen Domain-Containing Protein 1; Ficolin-1;

Entrez Gene ID

2219

UniProt ID

O00602

More Infomation

Xue, D., Tabib, T., Morse, C., Yang, Y., Domsic, R. T., Khanna, D., & Lafyatis, R. (2022). Expansion of Fcγ Receptor IIIa–Positive Macrophages, Ficolin 1–Positive Monocyte‐Derived Dendritic Cells, and Plasmacytoid Dendritic Cells Associated With Severe Skin Disease in Systemic Sclerosis. Arthritis & Rheumatology, 74(2), 329-341.

Luo, J., Wang, T., Wang, X., Shi, Y., Zhang, Y., Tian, J., & Gong, Y. (2022). Ficolin-3 may act as a tumour suppressor by recognising O-GlcNAcylation site in hepatocellular carcinoma. Medical Hypotheses, 166, 110899.

Li, Y., You, E. Q., Lin, W. H., Liu, X. N., Shen, D. P., Zhang, X. L., ... & Li, H. M. (2021). Association of ficolin‐1 and ficolin‐3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population. Journal of Clinical Laboratory Analysis, 35(4), e23732.

Elkoumi, M. A., Abdellatif, S. H., Mohamed, F. Y., Sherif, A. H., Elashkar, S. S., Saleh, R. M., ... & Zeidan, N. M. (2020). Ficolin‐1 gene (FCN1)− 144 C/A polymorphism is associated with adverse outcome of severe pneumonia in the under‐five Egyptian children: A multicenter study. Pediatric Pulmonology, 55(5), 1175-1183.

Pieczarka, C., Andrade, F. A., Catarino, S. J., Lidani, K. C. F., Bavia, L., Tizzot, R., ... & de Messias-Reason, I. J. (2020). Ficolin-1 and ficolin-3 polymorphisms and susceptibility to rheumatoid arthritis. Autoimmunity, 53(7), 400-407.

Katayama, M., Ota, K., Nagi-Miura, N., Ohno, N., Yabuta, N., Nojima, H., ... & Hirano, T. (2019). Ficolin-1 is a promising therapeutic target for autoimmune diseases. International immunology, 31(1), 23-32.

Catarino, S. J., Andrade, F. A., Boldt, A. B. W., Guilherme, L., & Messias-Reason, I. J. (2018). Sickening or healing the heart? The association of ficolin-1 and rheumatic fever. Frontiers in immunology, 9, 3009.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rhesus Recombinant FCN1 protein, hFc Tag (CAT#: V2LY-0526-LY9718)

Human Recombinant FCN1 protein, His Tag (CAT#: V2LY-0526-LY4144)

FCN1 Matched Antibody Pair (421) (CAT#: APMAB-421LY)

Antibody Pairs

FCN1 Matched Antibody Pair (421) (CAT#: APMAB-421LY)

Related Products

Human Recombinant FCN1 protein, His Tag (CAT#: V2LY-0526-LY4144)

Mouse Anti-FCN1 Recombinant Antibody (CBYCL-121) (CAT#: CBMAB-L0022-YC)

Rhesus Recombinant FCN1 protein, hFc Tag (CAT#: V2LY-0526-LY9718)

Mouse Anti-FCN1 Recombinant Antibody (CBXF-0475) (CAT#: CBMAB-F2292-CQ)

Mouse Anti-FCN1 Recombinant Antibody (CBXF-0474) (CAT#: CBMAB-F2291-CQ)

Mouse Anti-FCN1 Recombinant Antibody (CBXF-0476) (CAT#: CBMAB-F1433-CQ)

Rabbit Anti-FCN1 Recombinant Antibody (CBXF-1956) (CAT#: CBMAB-F0730-CQ)

FCN1 Matched Antibody Pair (421) (CAT#: APMAB-421LY)

Rabbit Anti-FCN1 Recombinant Antibody (CBXF-1373) (CAT#: CBMAB-F1208-CQ)

Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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