Sign in or Register   Sign in or Register
  |  

FCN1 Matched Antibody Pair (421) (APMAB-421LY)

This antibody pair set can be used for detecting and quantifying protein level of human FCN1.
See all FCN1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-FCN1 polyclonal antibody, 100 ug
Detection Antibody
Anti-FCN1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]
Alternative Names
Ficolin 1; Ficolin (Collagen/Fibrinogen Domain-Containing) 1; Ficolin-Alpha; Ficolin-A; M-Ficolin; FCNM; Ficolin (Collagen/Fibrinogen Domain Containing) 1; Collagen/Fibrinogen Domain-Containing Protein 1; Ficolin-1;
Entrez Gene ID
2219
UniProt ID
O00602

Xue, D., Tabib, T., Morse, C., Yang, Y., Domsic, R. T., Khanna, D., & Lafyatis, R. (2022). Expansion of Fcγ Receptor IIIa–Positive Macrophages, Ficolin 1–Positive Monocyte‐Derived Dendritic Cells, and Plasmacytoid Dendritic Cells Associated With Severe Skin Disease in Systemic Sclerosis. Arthritis & Rheumatology, 74(2), 329-341.

Luo, J., Wang, T., Wang, X., Shi, Y., Zhang, Y., Tian, J., & Gong, Y. (2022). Ficolin-3 may act as a tumour suppressor by recognising O-GlcNAcylation site in hepatocellular carcinoma. Medical Hypotheses, 166, 110899.

Li, Y., You, E. Q., Lin, W. H., Liu, X. N., Shen, D. P., Zhang, X. L., ... & Li, H. M. (2021). Association of ficolin‐1 and ficolin‐3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population. Journal of Clinical Laboratory Analysis, 35(4), e23732.

Elkoumi, M. A., Abdellatif, S. H., Mohamed, F. Y., Sherif, A. H., Elashkar, S. S., Saleh, R. M., ... & Zeidan, N. M. (2020). Ficolin‐1 gene (FCN1)− 144 C/A polymorphism is associated with adverse outcome of severe pneumonia in the under‐five Egyptian children: A multicenter study. Pediatric Pulmonology, 55(5), 1175-1183.

Pieczarka, C., Andrade, F. A., Catarino, S. J., Lidani, K. C. F., Bavia, L., Tizzot, R., ... & de Messias-Reason, I. J. (2020). Ficolin-1 and ficolin-3 polymorphisms and susceptibility to rheumatoid arthritis. Autoimmunity, 53(7), 400-407.

Katayama, M., Ota, K., Nagi-Miura, N., Ohno, N., Yabuta, N., Nojima, H., ... & Hirano, T. (2019). Ficolin-1 is a promising therapeutic target for autoimmune diseases. International immunology, 31(1), 23-32.

Catarino, S. J., Andrade, F. A., Boldt, A. B. W., Guilherme, L., & Messias-Reason, I. J. (2018). Sickening or healing the heart? The association of ficolin-1 and rheumatic fever. Frontiers in immunology, 9, 3009.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used FCN1 Matched Antibody Pair (421)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare