Mouse Aldh2 ELISA Kit (V2LY-0626-LY2006)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0073 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
56.5 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Aldehyde Dehydrogenase 2 Family (Mitochondrial)
Biological Process
Alcohol metabolic process Source: ProtInc
Carbohydrate metabolic process Source: ProtInc
Ethanol catabolic process Source: UniProtKB-UniPathway
Ethanol oxidation Source: Reactome
Cellular Location
Mitochondrion matrix

Zhu, Z. Y., Liu, Y. D., Gong, Y., Jin, W., Topchiy, E., Turdi, S., ... & Qin, X. (2021). Mitochondrial aldehyde dehydrogenase (ALDH2) rescues cardiac contractile dysfunction in an APP/PS1 murine model of Alzheimer’s disease via inhibition of ACSL4-dependent ferroptosis. Acta Pharmacologica Sinica, 1-11.

Chen, L., Wu, Y. T., Gu, X. Y., Xie, L. P., Fan, H. J., Tan, Z. B., ... & Sun, X. M. (2021). Magnolol, a natural aldehyde dehydrogenase-2 agonist, inhibits the proliferation and collagen synthesis of cardiac fibroblasts. Bioorganic & Medicinal Chemistry Letters, 43, 128045.

Suo, C., Yang, Y., Yuan, Z., Zhang, T., Yang, X., Qing, T., ... & Ye, W. (2019). Alcohol intake interacts with functional genetic polymorphisms of aldehyde dehydrogenase (ALDH2) and alcohol dehydrogenase (ADH) to increase esophageal squamous cell cancer risk. Journal of Thoracic Oncology, 14(4), 712-725.

Zhao, Y., Wang, B., Zhang, J., He, D., Zhang, Q., Pan, C., ... & Chen, Y. (2019). ALDH2 (Aldehyde Dehydrogenase 2) protects against hypoxia-induced pulmonary hypertension. Arteriosclerosis, thrombosis, and vascular biology, 39(11), 2303-2319.

Kimura, M., Yokoyama, A., & Higuchi, S. (2019). Aldehyde dehydrogenase-2 as a therapeutic target. Expert opinion on therapeutic targets, 23(11), 955-966.

Wang, Y., & He, W. (2018). Endogenous Mitochondrial Aldehyde Dehydrogenase-2 as an Antioxidant in Liver. In The Liver (pp. 247-259). Academic Press.

Miura, T., Nishinaka, T., Terada, T., & Yonezawa, K. (2017). Vasodilatory effect of nitroglycerin in Japanese subjects with different aldehyde dehydrogenase 2 (ALDH2) genotypes. Chemico-biological interactions, 276, 40-45.

Buchman, C. D., & Hurley, T. D. (2017). Inhibition of the aldehyde dehydrogenase 1/2 family by psoralen and coumarin derivatives. Journal of medicinal chemistry, 60(6), 2439-2455.

Nene, A., Chen, C. H., Disatnik, M. H., Cruz, L., & Mochly-Rosen, D. (2017). Aldehyde dehydrogenase 2 activation and coevolution of its εPKC-mediated phosphorylation sites. Journal of biomedical science, 24(1), 1-12.

Angenendt, L., Bormann, E., Mikesch, J. H., Herold, T., Metzeler, K. H., Bohlander, S. K., ... & Schliemann, C. (2017). Aldehyde Dehydrogenase 2 (ALDH2) Expression Predicts a Poor Prognosis in Acute Myeloid Leukemia. Blood, 130, 1386.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

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