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ALDH2

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]
Full Name
Aldehyde Dehydrogenase 2 Family (Mitochondrial)
Biological Process
Alcohol metabolic process Source: ProtInc
Carbohydrate metabolic process Source: ProtInc
Ethanol catabolic process Source: UniProtKB-UniPathway
Ethanol oxidation Source: Reactome
Cellular Location
Mitochondrion matrix
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Anti-ALDH2 antibodies

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Mouse Anti-ALDH2 Recombinant Antibody (3D12) (CBMAB-AP263LY)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 3D12
Application*: IP, E, WB
Datasheet SDS

Mouse Anti-ALDH2 Recombinant Antibody (4F10) (CBMAB-A0286-LY)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F10
Application*: SE, E
Datasheet SDS

Mouse Anti-ALDH2 Recombinant Antibody (2A7) (CBMAB-A0284-LY)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A7
Application*: WB, E
Datasheet SDS

Rabbit Anti-ALDH2 Recombinant Antibody (1J9I8) (CBMAB-A2276-YC)

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Target: ALDH2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 1J9I8
Application*: WB
Datasheet SDS

Mouse Anti-ALDH2 Recombinant Antibody (2C10) (CBMAB-A2275-YC)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2C10
Application*: WB, IF, E, IC
Datasheet SDS

Mouse Anti-ALDH2 Recombinant Antibody (1007902) (CBMAB-A2274-YC)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1007902
Application*: IC, IF, IH, WB
Datasheet SDS

Mouse Anti-ALDH2 Recombinant Antibody (1E5) (CBMAB-A2273-YC)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E5
Application*: E, WB
Datasheet SDS

Mouse Anti-ALDH2 Recombinant Antibody (CBT3686) (V2LY-0625-LY989)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBT3686
Application*: WB, IH, IC, F
Datasheet SDS

Mouse Anti-ALDH2 Recombinant Antibody (CBT3310) (V2LY-0625-LY988)

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Target: ALDH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBT3310
Application*: WB, IH, IC, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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