Human Recombinant PDE1B protein, GST Tag (V2LY-0526-LY6026)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
GST Tag
Protein Construction
This product is Human Recombinant PDE1B protein, GST Tag consist of Amino Acid: 1-536 and predicts a molecular mass of 89.2 kDa.
Molecule Mass
89.2 kDa
Sequence
Amino Acid: 1-536
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>94% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile Tirs, NaCl, Glycerol
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
phosphodiesterase 1B, calmodulin-dependent
Function
Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:8855339, PubMed:9419816, PubMed:15260978).
Has a preference for cGMP as a substrate (PubMed:9419816).
Biological Process
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Cellular response to granulocyte macrophage colony-stimulating factor stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Cellular response to macrophage colony-stimulating factor stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Locomotory behaviorIEA:Ensembl
Monocyte differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Regulation of dopamine metabolic processIEA:Ensembl
Regulation of neurotransmitter levelsIEA:Ensembl
Response to amphetamineIEA:Ensembl
Serotonin metabolic processIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Visual learningIEA:Ensembl
Cellular Location
Cytoplasm, cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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