Human Recombinant PTPRA, Active protein, GST Tag (V2LY-0526-LY6401)

Name: Human Recombinant PTPRA, Active protein, GST Tag
SKU: V2LY-0526-LY6401
Rating: 5 (1 reviews)

See all PTPRA antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant PTPRA, Active protein, GST Tag consist of Amino Acid: 174-802 and predicts a molecular mass of 96 kDa.

Molecule Mass

96 kDa

Sequence

Amino Acid: 174-802

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

Tris, NaCl, GSH

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

protein tyrosine phosphatase, receptor type, A

Function

Tyrosine protein phosphatase which is involved in integrin-mediated focal adhesion formation (By similarity).
Following integrin engagement, specifically recruits BCAR3, BCAR1 and CRK to focal adhesions thereby promoting SRC-mediated phosphorylation of BRAC1 and the subsequent activation of PAK and small GTPase RAC1 and CDC42 (By similarity).

Biological Process

Insulin receptor signaling pathwayIEA:Ensembl
Integrin-mediated signaling pathwayISS:UniProtKB
Modulation of chemical synaptic transmissionIEA:Ensembl
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Protein phosphorylationIEA:Ensembl
Regulation of focal adhesion assemblyISS:UniProtKB

Cellular Location

Cell membrane
Cell junction, focal adhesion
Localizes to focal adhesion sites following integrin engagement.

Topology

Extracellular: 20-151
Helical: 152-174
Cytoplasmic: 175-802

PTM

Integrin binding to extracellular matrix induces phosphorylation at Tyr-798 which induces PTPRA localization and recruitment of BCAR3, BCAR1 and CRK to focal adhesions.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant PTPRA, Active protein, GST Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant PTPRA protein, GST Tag (CAT#: V2LY-0526-LY6400)

Related Products

Mouse Anti-PTPRA Recombinant Antibody (5G3) (CAT#: CBMAB-P3451-YC)

Mouse Anti-PTPRA Recombinant Antibody (21/RPTPA) (CAT#: CBMAB-R0662-CN)

Human Recombinant PTPRA protein, GST Tag (CAT#: V2LY-0526-LY6400)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry