Human Recombinant PTPRF, Active protein, GST Tag (V2LY-0526-LY6418)

Name: Human Recombinant PTPRF, Active protein, GST Tag
SKU: V2LY-0526-LY6418
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant PTPRF, Active protein, GST Tag consist of Amino Acid: 1275-1897 and predicts a molecular mass of 93 kDa.

Molecule Mass

93 kDa

Sequence

Amino Acid: 1275-1897

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

PTPRF

Function

Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.

Biological Process

Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of receptor bindingManual Assertion Based On ExperimentIMP:UniProtKB
Neuron projection regenerationIEA:Ensembl
Peptidyl-tyrosine dephosphorylationManual Assertion Based On ExperimentIMP:UniProtKB
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of axon regenerationIEA:Ensembl
Synaptic membrane adhesionManual Assertion Based On ExperimentIDA:SynGO
Transmembrane receptor protein tyrosine phosphatase signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Membrane

Involvement in disease

Aplasia or hypoplasia of the breasts and/or nipples 2 (BNAH2):
A group of congenital deformities encompassing total absence of breasts and nipple (amastia), absence of the nipple (athelia), and absence of the mammary gland (amazia).

Topology

Extracellular: 30-1263
Helical: 1264-1284
Cytoplasmic: 1285-1907

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human PTPRF ELISA Kit (CAT#: V2LY-0626-LY5168)

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Rat Anti-PTPRF Recombinant Antibody (CBYJL-2332) (CAT#: CBMAB-L2633-YJ)

Rabbit Anti-PTPRF Recombinant Antibody (E8W3H) (CAT#: CBMAB-CP1349-LY)

Rabbit Anti-PTPRF Recombinant Antibody (E6W4X) (CAT#: CBMAB-CP1351-LY)

Mouse Anti-PTPRF Recombinant Antibody (CBYJL-2333) (CAT#: CBMAB-L2634-YJ)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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