Human Recombinant TPH1 protein, His Tag (V2LY-0526-LY7427)

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Basic Information

Expressed Host
E. coli
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant TPH1 protein, His Tag consist of Amino Acid: 2-444 and predicts a molecular mass of 52.7 kDa.
Molecule Mass
52.7 kDa
Sequence
Amino Acid: 2-444
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
TPH1 Gene(Protein Coding) Tryptophan Hydroxylase 1
Function
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.
Biological Process
Biological Process aromatic amino acid family metabolic process Source:InterPro
Biological Process bone remodeling Source:Ensembl
Biological Process circadian rhythm Source:Ensembl
Biological Process mammary gland alveolus development Source:Ensembl
Biological Process negative regulation of ossification Source:Ensembl
Biological Process platelet degranulation Source:UniProtKB
Biological Process positive regulation of fat cell differentiation Source:Ensembl
Biological Process regulation of hemostasis Source:UniProtKB
Biological Process response to immobilization stress Source:Ensembl
Biological Process serotonin biosynthetic process Source:UniProtKB
Cellular Location
cytosol
neuron projection
PTM
Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation.
Phosphorylated; triggering degradation by the proteasome.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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