Mouse Ltb ELISA Kit (V2LY-0626-LY1419)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0031 ng/mL
Detection Range
0.007-1.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
32.3 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Lymphotoxin Beta
Function
Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
Biological Process
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Gene expressionIEA:Ensembl
Immune responseIEA:InterPro
Lymph node developmentIEA:Ensembl
Positive regulation of interleukin-12 productionISS:UniProtKB
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Skin developmentIEA:Ensembl
Cellular Location
Membrane
Topology
Cytoplasmic: 1-18
Helical: 19-48
Extracellular: 49-244

Sun, L., Hu, L., Chen, P., Li, Y., Tu, J., & Chen, J. (2023). Long Non-Coding RNA AL928768. 3 Promotes Rheumatoid Arthritis Fibroblast-Like Synoviocytes Proliferation, Invasion and Inflammation, While Inhibits Apoptosis Via Activating Lymphotoxin Beta Mediated NF-κB Signaling Pathway. Inflammation, 1-14.

Harris, C. S., Miaskowski, C. A., Conley, Y. P., Hammer, M. J., Dhruva, A. A., Levine, J. D., ... & Kober, K. M. (2023). Gastrointestinal Symptom Cluster is Associated With Epigenetic Regulation of Lymphotoxin Beta in Oncology Patients Receiving Chemotherapy. Biological Research For Nursing, 25(1), 51-64.

Feng, X., Sun, R., Lee, M., Chen, X., Guo, S., Geng, H., ... & Pereira, J. P. (2023). Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin beta receptor signaling. Elife, 12, e83533.

Monaco, G., Khavaran, A., Gasull, A. D., Cahueau, J., Diebold, M., Chhatbar, C., ... & Sankowski, R. (2022). Transcriptome Analysis Identifies Accumulation of Natural Killer Cells with Enhanced Lymphotoxin-β Expression during Glioblastoma Progression. Cancers, 14(19), 4915.

Huang, R., Zeng, Z., Yan, P., Yin, H., Zhu, X., Hu, P., ... & Huang, Z. (2021). Targeting Lymphotoxin Beta and Paired Box 5: a potential therapeutic strategy for soft tissue sarcoma metastasis. Cancer Cell International, 21(1), 1-19.

Das, R., Coupar, J., Clavijo, P. E., Saleh, A., Cheng, T. F., Yang, X., ... & Chen, Z. (2019). Lymphotoxin‐β receptor‐NIK signaling induces alternative RELB/NF‐κB2 activation to promote metastatic gene expression and cell migration in head and neck cancer. Molecular carcinogenesis, 58(3), 411-425.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant LTB protein, His Tag (CAT#: V2LY-0526-LY1600)

Human LTB ELISA Kit (CAT#: V2LY-0626-LY513)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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