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MSI2 Matched Antibody Pair (758) (APMAB-758LY)

This antibody pair set can be used for detecting and quantifying protein level of human MSI2.
See all MSI2 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-MSI2 monoclonal, IgG2b antibody, 100 ug
Detection Antibody
Anti-MSI2 Biotinylated mouse monoclonal, IgG2a antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
Alternative Names
Musashi RNA Binding Protein 2; Musashi-2; RNA-Binding Protein Musashi Homolog 2; Musashi Homolog 2 (Drosophila); Musashi Homolog 2; MSI2H;
Entrez Gene ID
124540
UniProt ID
Q96DH6

Sicking, M., Falke, I., Löblein, M. T., Eich, H. T., Götte, M., Greve, B., & Troschel, F. M. (2023). The Musashi RNA-binding proteins in female cancers: insights on molecular mechanisms and therapeutic relevance. Biomarker Research, 11(1), 76.

Suo, J., Zou, S., Wang, J., Han, Y., Zhang, L., Lv, C., ... & Zou, W. (2022). The RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPARγ signaling. Bone Research, 10(1), 31.

Wang, J., Lan, L., Wu, X., Xu, L., & Miao, Y. (2022). Mechanism of RNA recognition by a Musashi RNA-binding protein. Current Research in Structural Biology, 4, 10-20.

Löblein, M. T., Falke, I., Eich, H. T., Greve, B., Götte, M., & Troschel, F. M. (2021). Dual knockdown of musashi RNA-binding proteins MSI-1 and MSI-2 attenuates putative cancer stem cell characteristics and therapy resistance in ovarian cancer cells. International Journal of Molecular Sciences, 22(21), 11502.

Sun, J., Sheng, W., Ma, Y., & Dong, M. (2021). Potential role of musashi-2 RNA-binding protein in cancer EMT. OncoTargets and therapy, 1969-1980.

Li, M., Li, A. Q., Zhou, S. L., Lv, H., Wei, P., & Yang, W. T. (2020). RNA-binding protein MSI2 isoforms expression and regulation in progression of triple-negative breast cancer. Journal of Experimental & Clinical Cancer Research, 39, 1-18.

Forouzanfar, M., Lachinani, L., Dormiani, K., Nasr-Esfahani, M. H., Gure, A. O., & Ghaedi, K. (2020). Intracellular functions of RNA-binding protein, Musashi1, in stem and cancer cells. Stem Cell Research & Therapy, 11, 1-10.

Zhao, J., Zhang, Y., Liu, X. S., Zhu, F. M., Xie, F., Jiang, C. Y., ... & Han, B. M. (2020). RNA‐binding protein Musashi2 stabilizing androgen receptor drives prostate cancer progression. Cancer Science, 111(2), 369-382.

Troschel, F. M., Minte, A., Ismail, Y. M., Kamal, A., Abdullah, M. S., Ahmed, S. H., ... & Greve, B. (2020). Knockdown of musashi RNA binding proteins decreases radioresistance but enhances cell motility and invasion in triple-negative breast cancer. International Journal of Molecular Sciences, 21(6), 2169.

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For research use only. Not intended for any clinical use.

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