MSI2

This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]

Full Name

Musashi RNA Binding Protein 2

Function

RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

Biological Process

Stem cell development Source: Ensembl

Cellular Location

Cytoplasm
Note: Associated with polysomes.

Involvement in disease

Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).

PTM

Phosphorylated.

Anti-MSI2 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-MSI2 Recombinant Antibody (CBT899) (V2LY-0625-LY3187)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBT899

Application*: WB, P, IF, E

Mouse Anti-MSI2 Recombinant Antibody (CBT3122) (V2LY-0625-LY2552)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT3122

Application*: WB, IH

Mouse Anti-MSI2 Recombinant Antibody (CBT4315) (V2LY-0625-LY1367)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT4315

Application*: WB

MSI2 Matched Antibody Pair (758) (APMAB-758LY)

Datasheet

SDS

Target: MSI2

Specificity: Human

Mouse Anti-MSI2 Recombinant Antibody (3B6) (CBMAB-A5619-LY)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 3B6

Application*: WB, E

Mouse Anti-MSI2 Recombinant Antibody (1F2) (CBMAB-A5615-LY)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1F2

Application*: WB, E

Rabbit Anti-MSI2 Recombinant Antibody (CBFYM-2641) (CBMAB-M2830-FY)

Datasheet

SDS

Target: MSI2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBFYM-2641

Application*: WB, P, IF, F

Mouse Anti-MSI2 (AA 1-328) Recombinant Antibody (CBFYM-2640) (CBMAB-M2829-FY)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-2640

Application*: E, siRNA, WB

Mouse Anti-MSI2 Recombinant Antibody (CBFYM-2639) (CBMAB-M2828-FY)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-2639

Application*: IF, P, WB

Rabbit Anti-MSI2 Recombinant Antibody (CBFYM-0283) (CBMAB-M0348-FY)

Datasheet

SDS

Target: MSI2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Rat

Clone: CBFYM-0283

Application*: IF

Mouse Anti-MSI2 Recombinant Antibody (CBFYM-0227) (CBMAB-M0271-FY)

Datasheet

SDS

Target: MSI2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYM-0227

Application*: F

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)