MSI2

This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
Full Name
Musashi RNA Binding Protein 2
Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Biological Process
Stem cell development Source: Ensembl
Cellular Location
Cytoplasm
Note: Associated with polysomes.
Involvement in disease
Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).
PTM
Phosphorylated.
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Anti-MSI2 antibodies

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Mouse Anti-MSI2 Recombinant Antibody (CBT899) (V2LY-0625-LY3187)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT899
Application*: WB, P, IF, E
Datasheet SDS

Mouse Anti-MSI2 Recombinant Antibody (CBT3122) (V2LY-0625-LY2552)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3122
Application*: WB, IH
Datasheet SDS

Mouse Anti-MSI2 Recombinant Antibody (CBT4315) (V2LY-0625-LY1367)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4315
Application*: WB
Datasheet SDS

MSI2 Matched Antibody Pair (758) (APMAB-758LY)

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Target: MSI2
Specificity: Human
Datasheet SDS

Mouse Anti-MSI2 Recombinant Antibody (3B6) (CBMAB-A5619-LY)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3B6
Application*: WB, E
Datasheet SDS

Mouse Anti-MSI2 Recombinant Antibody (1F2) (CBMAB-A5615-LY)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F2
Application*: WB, E
Datasheet SDS

Rabbit Anti-MSI2 Recombinant Antibody (CBFYM-2641) (CBMAB-M2830-FY)

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Target: MSI2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYM-2641
Application*: WB, P, IF, F
Datasheet SDS

Mouse Anti-MSI2 (AA 1-328) Recombinant Antibody (CBFYM-2640) (CBMAB-M2829-FY)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2640
Application*: E, siRNA, WB
Datasheet SDS

Mouse Anti-MSI2 Recombinant Antibody (CBFYM-2639) (CBMAB-M2828-FY)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2639
Application*: IF, P, WB
Datasheet SDS

Rabbit Anti-MSI2 Recombinant Antibody (CBFYM-0283) (CBMAB-M0348-FY)

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Target: MSI2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYM-0283
Application*: IF
Datasheet SDS

Mouse Anti-MSI2 Recombinant Antibody (CBFYM-0227) (CBMAB-M0271-FY)

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Target: MSI2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-0227
Application*: F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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