Rat Timp1 ELISA Kit (V2LY-0626-LY716)

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Tested Data
Datasheet
SDS
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Basic Information

Sensitivity
0.02 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
23.8 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TIMP1 Gene(Protein Coding) TIMP Metallopeptidase Inhibitor 1
Function
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
Biological Process
Biological Process agingSource:Ensembl
Biological Process cartilage developmentSource:Ensembl
Biological Process cell activationSource:Ensembl
Biological Process cellular response to UV-ASource:UniProtKB1 Publication
Biological Process connective tissue replacement involved in inflammatory response wound healingSource:Ensembl
Biological Process negative regulation of apoptotic processSource:Ensembl
Biological Process negative regulation of catalytic activitySource:UniProtKB1 Publication
Biological Process negative regulation of endopeptidase activitySource:UniProtKB1 Publication
Biological Process negative regulation of membrane protein ectodomain proteolysisSource:UniProtKB1 Publication
Biological Process negative regulation of metallopeptidase activitySource:UniProtKB1 Publication
Biological Process negative regulation of trophoblast cell migrationSource:BHF-UCL1 Publication
Biological Process positive regulation of cell population proliferationSource:UniProtKB1 Publication
Biological Process regulation of integrin-mediated signaling pathwaySource:UniProtKB1 Publication
Biological Process response to cytokineSource:GO_Central1 Publication
Biological Process response to hormoneSource:GO_Central1 Publication
Biological Process response to organic substanceSource:GO_Central1 Publication
Biological Process response to peptide hormoneSource:Ensembl
Cellular Location
Secreted
PTM
The activity of TIMP1 is dependent on the presence of disulfide bonds.
N-glycosylated.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant TIMP1 protein, hFc Tag (CAT#: V2LY-0526-LY7238)

Human Recombinant TIMP1 protein, His Tag (CAT#: V2LY-0526-LY7239)

Human Recombinant TIMP1 protein (CAT#: V2LY-0526-LY7240)

Mouse Recombinant TIMP1 protein (CAT#: V2LY-0526-LY8983)

Rat Recombinant TIMP1 protein (CAT#: V2LY-0526-LY9608)

Horse TIMP1 ELISA Kit (CAT#: V2LY-0626-LY439)

Dog TIMP1 ELISA Kit (CAT#: V2LY-0626-LY786)

TIMP1 Matched Antibody Pair (1207) (CAT#: APMAB-1207LY)

Antibody Pairs

TIMP1 Matched Antibody Pair (1207) (CAT#: APMAB-1207LY)

Related Products

Mouse Anti-TIMP1 Recombinant Antibody (CBYJT-3194) (CAT#: CBMAB-T2469-YJ)

Mouse Anti-TIMP1 Recombinant Antibody (CB293A) (CAT#: CBMAB-CA293LY)

Horse TIMP1 ELISA Kit (CAT#: V2LY-0626-LY439)

Dog TIMP1 ELISA Kit (CAT#: V2LY-0626-LY786)

Human Recombinant TIMP1 protein, hFc Tag (CAT#: V2LY-0526-LY7238)

Mouse Anti-Timp1 Recombinant Antibody (CBYJT-3208) (CAT#: CBMAB-T2483-YJ)

Rabbit Anti-TIMP1 Recombinant Antibody (D10E6) (CAT#: CBMAB-CP2775-LY)

Human Recombinant TIMP1 protein, His Tag (CAT#: V2LY-0526-LY7239)

Mouse Anti-TIMP1 Recombinant Antibody (CBYJT-3191) (CAT#: CBMAB-T2465-YJ)

Mouse Anti-TIMP1 Recombinant Antibody (4E7) (CAT#: CBMAB-A9107-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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