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HA

Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A. Influenza virus A is a genus of the Orthomyxoviridae family of viruses. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics. Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses. The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N1 to N11). H17 was isolated from fruit bats in 2012. H18N11 was discovered in a Peruvian bat in 2013. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species. A filtered and purified influenza A vaccine for humans has been developed, and many countries have stockpiled it to allow a quick administration to the population in the event of an avian influenza pandemic. Avian influenza is sometimes called avian flu, and colloquially, bird flu. In 2011, researchers reported the discovery of an antibody effective against all types of the influenza A virus. Influenza haemagglutinin is a glycoprotein found on the surface of influenza viruses. It is responsible for binding the virus to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes. It is also responsible for the fusion of the viral envelope with the endosome membrane, after the pH has been reduced. The name "hemagglutinin" comes from the protein's ability to cause red blood cells to clump together in vitro.

Anti-HA antibodies

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Mouse Anti-HA Recombinant Antibody (12CA5) (CBMAB-1178-LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG2b
Clone: 12CA5
Application*: WB, E, IP, IF

Mouse Anti-HA Recombinant Antibody (7H12F6) (CBMAB-AO542LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Virus
Clone: 7H12F6
Application*: ELISA, WB

Mouse Anti-HA Recombinant Antibody (3E9H5) (CBMAB-AO543LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Virus
Clone: 3E9H5
Application*: ELISA

Mouse Anti-HA Recombinant Antibody (A141) (CBMAB-AP2939LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG
Specificity: Virus
Clone: A141
Application*: ELISA, WB

Mouse Anti-HA Recombinant Antibody (A145) (CBMAB-AP2943LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG
Specificity: Virus
Clone: A145
Application*: ELISA, WB

Mouse Anti-HA Recombinant Antibody (A140) (CBMAB-AP2938LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG
Specificity: Virus
Clone: A140
Application*: ELISA

Mouse Anti-HA Recombinant Antibody (A142) (CBMAB-AP2940LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG
Specificity: Virus
Clone: A142
Application*: ELISA

Mouse Anti-HA Recombinant Antibody (A143) (CBMAB-AP2941LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG
Specificity: Virus
Clone: A143
Application*: ELISA, WB

Mouse Anti-HA Recombinant Antibody (A144) (CBMAB-AP2942LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG
Specificity: Virus
Clone: A144
Application*: ELISA, WB

Mouse Anti-HA Recombinant Antibody (A146) (CBMAB-AP2944LY)

Target: HA
Host: Mouse
Antibody Isotype: IgG
Specificity: Virus
Clone: A146
Application*: ELISA, WB

H7N9 subtype HA Peptide (PRYVKQRSLLLATG) (PEP-078470CQ)

Target: HA
Specificity: H7N9 subtype

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (YVEDTKIDLWSYNAEL) (PEP-078468CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (TNEKFHQIEKEFSEVE) (PEP-078467CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (SYNAELLVALENQHTI) (PEP-078466CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (QDLEKYVEDTKIDLWS) (PEP-078463CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (LLVALENQHTIDLTDS) (PEP-078461CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (LIEKTNEKFHQIEKEF) (PEP-078458CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (HQIEKEFSEVEGRIQD) (PEP-078454CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (EGRIQDLEKYVEDTKI) (PEP-078451CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype Influenza A virus (A/Hong Kong(H3N2)) HA Peptide (EFSEVEGRIQDLEKYV) (PEP-078450CQ)

Target: HA
Specificity: H3N2 subtype FLUAV (A/Hong Kong(H3N2))

H3N2 subtype HA Peptide (PRYVKQNTLKLATG) (PEP-078447CQ)

Target: HA
Specificity: H3N2 subtype

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (GRINYYWTL) (PEP-174171CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (CYPGYFADY) (PEP-174170CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (PNHNTNGVTAACSHE) (PEP-174744CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (PNHNTNGVTAA) (PEP-174743CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (TDADTICIGY) (PEP-174169CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (LEDSHNGKL) (PEP-174168CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (AGRMNYYWTL) (PEP-174546CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (PLQLGKCNIAGWLLG) (PEP-174742CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (PLLPVRSWSYIVETP) (PEP-174741CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (KGIAPLQL) (PEP-174167CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (IAPWYAFAL) (PEP-174166CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NYNRRFTPEIAERPK) (PEP-174740CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NTVIEKMNIQFTAVG) (PEP-174739CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (WLTEKEGSYP) (PEP-174544CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (VTGLRNIPSIQSR) (PEP-174543CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (FEIFPKESSW) (PEP-174165CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (EELREQLSSV) (PEP-174164CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NTPSIQSRGLFGAIA) (PEP-174738CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NSENGICYPGDFIDY) (PEP-174737CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (TYNAELLVL) (PEP-174542CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (SFERFEIFPKE) (PEP-174541CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (DTICIGYHA) (PEP-174163CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (DADTICIGY) (PEP-174162CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NPECDPLLPVRSWSY) (PEP-174736CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NNAKEIGNGCFEFYH) (PEP-174735CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Harbin/1/1988(H1N2)) HA Peptide (ATDADTICI) (PEP-174161CQ)

Target: HA
Specificity: FLUAV (A/Harbin/1/1988(H1N2))

Influenza A virus (A/England/878/1969(H3N2)) HA Peptide (NCTLIDALLGDPH) (PEP-174132CQ)

Target: HA
Specificity: FLUAV (A/England/878/1969(H3N2))

Influenza A virus (A/chicken/Pennsylvania/1/1983(H5N2)) HA Peptide (IYSTVASSL) (PEP-174119CQ)

Target: HA
Specificity: FLUAV (A/chicken/Pennsylvania/1/1983(H5N2))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (PVTIGECPK) (PEP-174540CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (NVKNLYEKVK) (PEP-174539CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NIYQNENAYVSVVTS) (PEP-174734CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NHNTNGVTAAC) (PEP-174733CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (LTEKEGSYPK) (PEP-174538CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (IPSIQSRGL) (PEP-174537CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NGVTAACSHEGKSSF) (PEP-174732CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) HA Peptide (NGSLQCRICI) (PEP-174731CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/34/Mount Sinai(H1N1))

Influenza A virus (A/California/07/2009(H1N1)) HA Peptide (SVIEKMNTQFTAV) (PEP-174110CQ)

Target: HA
Specificity: FLUAV (A/California/07/2009(H1N1))

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) HA Peptide (GVTAACSHAGK) (PEP-174536CQ)

Target: HA
Specificity: FLUAV (A/Puerto Rico/8/1934(H1N1))

Influenza A virus (A/budgerigar/Hokkaido/1/1977(H4N6)) HA Peptide (RGLFGAIAGF) (PEP-173789CQ)

Target: HA
Specificity: FLUAV (A/budgerigar/Hokkaido/1/1977(H4N6))
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For research use only. Not intended for any clinical use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)