ACOT11

ACOT11 is a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Full Name
Acyl-CoA Thioesterase 11
Function
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
Biological Process
Acyl-CoA metabolic process
Fatty acid metabolic process
Intracellular signal transduction
Negative regulation of cold-induced thermogenesis
Response to cold
Response to temperature stimulus
Cellular Location
Mitochondrion matrix; Cytoplasm
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Anti-ACOT11 antibodies

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Mouse Anti-ACOT11 Recombinant Antibody (V2-179336) (CBMAB-A0636-YC)

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Target: ACOT11
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-179336
Application*: WB, E, IH, P
Datasheet SDS

Mouse Anti-ACOT11 Recombinant Antibody (V2-179335) (CBMAB-A0635-YC)

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Target: ACOT11
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-179335
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ACOT11 Recombinant Antibody (V2-179334) (CBMAB-A0634-YC)

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Target: ACOT11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-179334
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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