AFP

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Full Name
Alpha Fetoprotein
Alternative Names
Alpha Fetoprotein; Alpha-1-Fetoprotein; Alpha-Fetoglobulin; HPAFP; Alpha-Fetoprotein; AFPD; FETA;
Function
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Biological Process
Cellular protein metabolic process
Post-translational protein modification
Cellular Location
Secreted
Involvement in disease
Alpha-fetoprotein deficiency (AFPD): A benign condition characterized by undetectable AFP levels in the amniotic fluid. Affected individuals are asymptomatic and present normal development.
Alpha-fetoprotein, hereditary persistence (HPAFP): A benign autosomal dominant condition characterized by continued expression of alpha-fetoprotein in adult life.
PTM
Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
Sulfated.
View more

Anti-AFP antibodies

+ Filters
Loading...

Mouse Anti-AFP Recombinant Antibody (EC9) (V2LY-0624-LY9)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: EC9
Application*: WB, P, IF
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (V2-634168) (CBMAB-AP202LY)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-634168
Application*: WB
Datasheet SDS

Mouse Anti-AFP Monoclonal Antibody (V2-632688) (CBMAB-R0434-FY)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: V2-632688
Application*: FC, IF, WB
Datasheet SDS

Mouse Anti-AFP Monoclonal Antibody (V2-632687) (CBMAB-R0433-FY)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: V2-632687
Application*: FC, IF
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (V2-180149) (CBMAB-A1565-YC)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: V2-180149
Application*: E, IP, IH, WB
Datasheet SDS

Rabbit Anti-AFP Recombinant Antibody (V2-180147) (CBMAB-A1563-YC)

Go to compareCompare
Target: AFP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: V2-180147
Application*: WB, E, IP
Datasheet SDS

Rabbit Anti-AFP Recombinant Antibody (V2-180140) (CBMAB-A1555-YC)

Go to compareCompare
Target: AFP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: V2-180140
Application*: WB, IP
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (V2-180098) (CBMAB-A1508-YC)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180098
Application*: E, IF, IP, WB
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (V2-180091) (CBMAB-A1501-YC)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: V2-180091
Application*: E, WB
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (V2-163277) (CBMAB-F3436-CQ)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: V2-163277
Application*: E, IH, WB
Datasheet SDS

Human Recombinant AFP protein, His Tag (V2LY-0526-LY2054)

Go to compareCompare
Target: AFP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-609
Tag: His Tag
Datasheet SDS

Human Recombinant AFP protein, Biotin Conjugated, His & AVI Tag (V2LY-0526-LY2053)

Go to compareCompare
Target: AFP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-609
Tag: His & AVI Tag
Datasheet SDS

Human Recombinant AFP protein, hFc Tag (V2LY-0526-LY2052)

Go to compareCompare
Target: AFP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-609
Tag: hFc Tag
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (
8E10) (V2LY-0725-LY244)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 8E10
Application*: E, WB
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (
16G2) (V2LY-0725-LY47)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 16G2
Application*: E, WB
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (CBT3) (V2LY-0625-LY3879)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT3
Application*: WB, P, IF, IC
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (CBT138) (V2LY-0625-LY3771)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT138
Application*: WB, E
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (CBT2176) (V2LY-0625-LY2374)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2176
Application*: WB
Datasheet SDS

Mouse Anti-AFP Recombinant Antibody (CBT4562) (V2LY-0625-LY1998)

Go to compareCompare
Target: AFP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT4562
Application*: IH, F
Datasheet SDS

AFP Matched Antibody Pair (030) (APMAB-030LY)

Go to compareCompare
Target: AFP
Specificity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.