AKR1B10

AKR1B10 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
Full Name
Aldo-Keto Reductase Family 1 Member B10
Function
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols (PubMed:9565553, PubMed:18087047, PubMed:12732097, PubMed:19013440, PubMed:19563777). Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal (PubMed:12732097, PubMed:18087047). Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) (PubMed:19013440, PubMed:19563777). Displays no reductase activity towards glucose (PubMed:12732097).
Biological Process
Cellular detoxification of aldehyde Source: UniProtKB
Daunorubicin metabolic process Source: UniProtKB
Doxorubicin metabolic process Source: UniProtKB
Farnesol catabolic process Source: UniProtKB
Retinoid metabolic process Source: UniProtKB
Cellular Location
Lysosome; Secreted. Secreted through a lysosome-mediated non-classical pathway.
View more

Anti-AKR1B10 antibodies

+ Filters
Loading...

Rabbit Anti-AKR1B10 Recombinant Antibody (V2-180473) (CBMAB-A1981-YC)

Go to compareCompare
Target: AKR1B10
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: V2-180473
Application*: WB, IC, IF
Datasheet SDS

Rabbit Anti-AKR1B10 Recombinant Antibody (V2-180472) (CBMAB-A1980-YC)

Go to compareCompare
Target: AKR1B10
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: V2-180472
Application*: WB, F, IC, IF
Datasheet SDS

Mouse Anti-AKR1B10 Recombinant Antibody (V2-180471) (CBMAB-A1979-YC)

Go to compareCompare
Target: AKR1B10
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180471
Application*: E
Datasheet SDS

Mouse Anti-AKR1B10 Recombinant Antibody (V2-180470) (CBMAB-A1978-YC)

Go to compareCompare
Target: AKR1B10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-180470
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-AKR1B10 Recombinant Antibody (V2-180469) (CBMAB-A1977-YC)

Go to compareCompare
Target: AKR1B10
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180469
Application*: E, IC, IF, P, WB
Datasheet SDS

Human AKR1B10 ELISA Kit (V2LY-0626-LY3803)

Go to compareCompare
Target: AKR1B10
Sensitivity: 0.021 ng/mL
Detection Range: 0.05-10 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.