ANXA3
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]
Full Name
Annexin A3
Function
Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.
Biological Process
Animal organ regeneration Source: Ensembl
Defense response to bacterium Source: UniProtKB
Hippocampus development Source: Ensembl
Neutrophil degranulation Source: UniProtKB
Phagocytosis Source: UniProtKB
Positive regulation of angiogenesis Source: UniProtKB
Positive regulation of DNA-binding transcription factor activity Source: UniProtKB
Positive regulation of DNA metabolic process Source: Ensembl
Positive regulation of endothelial cell migration Source: UniProtKB
Response to glucocorticoid Source: Ensembl
Response to growth factor Source: Ensembl
Defense response to bacterium Source: UniProtKB
Hippocampus development Source: Ensembl
Neutrophil degranulation Source: UniProtKB
Phagocytosis Source: UniProtKB
Positive regulation of angiogenesis Source: UniProtKB
Positive regulation of DNA-binding transcription factor activity Source: UniProtKB
Positive regulation of DNA metabolic process Source: Ensembl
Positive regulation of endothelial cell migration Source: UniProtKB
Response to glucocorticoid Source: Ensembl
Response to growth factor Source: Ensembl
Cellular Location
Extracellular exosome; Plasma membrane; Axon; Cytoplasm; Dendrite; Membrane; Neuronal cell body; Phagocytic vesicle membrane; Specific granule
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Anti-ANXA3 antibodies
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Target: ANXA3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CAP138
Application*: IH, WB
Target: ANXA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYC-A630
Application*: E, WB, P, IF, IP
Target: ANXA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYC-A629
Application*: E, WB, P, IF, IP
Target: ANXA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4F1
Application*: E, RNAi, WB
Target: ANXA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E2
Application*: E, IP, WB
Target: ANXA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: A2907
Application*: WB, IH
Target: ANXA3
Sensitivity: 0.055 ng/mL
Detection Range: 0.1-35 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Anxa3
Sensitivity: 0.0095 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: ANXA3
Specificity: Human
Target: ANXA3
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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