BACH1
BACH1-AS1 (BACH1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.
Full Name
BACH1
Function
Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK (By similarity).
Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498).
Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498).
Biological Process
DNA repair Source: CACAO
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Regulation of transcription from RNA polymerase II promoter in response to hypoxia Source: UniProtKB
Regulation of transcription involved in G1/S transition of mitotic cell cycle Source: UniProtKB
Regulation of transcription involved in G2/M transition of mitotic cell cycle Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Regulation of transcription from RNA polymerase II promoter in response to hypoxia Source: UniProtKB
Regulation of transcription involved in G1/S transition of mitotic cell cycle Source: UniProtKB
Regulation of transcription involved in G2/M transition of mitotic cell cycle Source: UniProtKB
Cellular Location
Nucleus
PTM
Ubiquitinated by the SCF(FBXL17) complex, leading to its degradation by the proteasome.
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Anti-BACH1 antibodies
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Target: BACH1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: E4E7B
Application*: WB, IP
Target: BACH1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 1B8
Application*: WB, E
Target: BACH1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: F9
Application*: WB, IF, IP, E
Target: BACH1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0124
Application*: WB, FC, IH
Target: BACH1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-0123
Application*: WB, IP, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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