CDA
CDA (Cytidine Deaminase) is a Protein Coding gene. Diseases associated with CDA include Refractory Hematologic Cancer and Refractory Hairy Cell Leukemia. Among its related pathways are Pyrimidine metabolism (KEGG) and Innate Immune System. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and hydrolase activity.
Full Name
Cytidine Deaminase
Function
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Biological Process
Cell surface receptor signaling pathway Source: UniProtKB
Cytidine deamination Source: UniProtKB
Cytosine metabolic process Source: UniProtKB
Negative regulation of cell growth Source: UniProtKB
Negative regulation of nucleotide metabolic process Source: UniProtKB
Neutrophil degranulation Source: Reactome
Pyrimidine-containing compound salvage Source: UniProtKB
Pyrimidine nucleoside salvage Source: Reactome
Cytidine deamination Source: UniProtKB
Cytosine metabolic process Source: UniProtKB
Negative regulation of cell growth Source: UniProtKB
Negative regulation of nucleotide metabolic process Source: UniProtKB
Neutrophil degranulation Source: Reactome
Pyrimidine-containing compound salvage Source: UniProtKB
Pyrimidine nucleoside salvage Source: Reactome
Cellular Location
Cytosol; Extracellular region; Ficolin-1-rich granule lumen; Secretory granule lumen; Tertiary granule lumen
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Anti-CDA antibodies
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Target: CDA
Sensitivity: 0.0054 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Cda
Sensitivity: 0.0097 ng/mL
Detection Range: 0.02-6 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CDA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: C4871
Application*: WB, IF, IP, E, P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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