CTSA

CTSA (Cathepsin A) is a Protein Coding gene. Diseases associated with CTSA include Galactosialidosis and Glycoproteinosis. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include enzyme activator activity and serine-type carboxypeptidase activity.
Full Name
Cathepsin A
Function
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
Biological Process
Glycosphingolipid metabolic process Source: Reactome
Intracellular protein transport Source: ProtInc
Negative regulation of chaperone-mediated autophagy Source: ParkinsonsUK-UCL
Neutrophil degranulation Source: Reactome
Proteolysis Source: ParkinsonsUK-UCL
Regulation of chaperone-mediated autophagy Source: ParkinsonsUK-UCL
Regulation of protein stability Source: ParkinsonsUK-UCL
Cellular Location
Lysosome
Involvement in disease
Galactosialidosis (GSL):
A lysosomal storage disease associated with a combined deficiency of beta-galactosidase and neuraminidase, secondary to a defect in cathepsin A. All patients have clinical manifestations typical of a lysosomal disorder, such as coarse facies, cherry red spots, vertebral changes, foam cells in the bone marrow, and vacuolated lymphocytes. Three phenotypic subtypes are recognized. The early infantile form is associated with fetal hydrops, edema, ascites, visceromegaly, skeletal dysplasia, and early death. The late infantile type is characterized by hepatosplenomegaly, growth retardation, cardiac involvement, and a normal or mildly affected mental state. The juvenile/adult form is characterized by myoclonus, ataxia, angiokeratoma, mental retardation, neurologic deterioration, absence of visceromegaly, and long survival.
View more

Anti-CTSA antibodies

+ Filters
Loading...

Mouse Anti-CTSA Recombinant Antibody (CBXC-0989) (CBMAB-C1251-CQ)

Go to compareCompare
Target: CTSA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0989
Application*: E
Datasheet SDS

Rat Anti-CTSA Recombinant Antibody (4A12) (CBMAB-C6560-LY)

Go to compareCompare
Target: CTSA
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 4A12
Application*: IH, WB
Datasheet SDS

Mouse Anti-CTSA Recombinant Antibody (CBCNC-467) (V2LY-0125-LY390)

Go to compareCompare
Target: CTSA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNC-467
Application*: WB, IP
Datasheet SDS

Mouse Anti-CTSA Recombinant Antibody (CBYY-C2307) (V2LY-0125-LY388)

Go to compareCompare
Target: CTSA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2307
Application*: E
Datasheet SDS

Rat Anti-CTSA Recombinant Antibody (CBFYC-2428) (V2LY-0125-LY387)

Go to compareCompare
Target: CTSA
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYC-2428
Application*: WB, IP
Datasheet SDS

Mouse Anti-CTSA Recombinant Antibody (CBFYC-2427) (V2LY-0125-LY386)

Go to compareCompare
Target: CTSA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-2427
Application*: WB, IP
Datasheet SDS

Rat Anti-CTSA Recombinant Antibody (CBFYC-2424) (V2LY-0125-LY385)

Go to compareCompare
Target: CTSA
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYC-2424
Application*: IP, IH
Datasheet SDS

Mouse Anti-CTSA Recombinant Antibody (CBFYC-2423) (V2LY-0125-LY384)

Go to compareCompare
Target: CTSA
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBFYC-2423
Application*: WB
Datasheet SDS

Rabbit Anti-CTSA Recombinant Antibody (108) (V2LY-0125-LY382)

Go to compareCompare
Target: CTSA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 108
Application*: E, IF
Datasheet SDS

Rabbit Anti-CTSA Recombinant Antibody (104) (V2LY-0125-LY381)

Go to compareCompare
Target: CTSA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 104
Application*: E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry