loading...

DHRS9

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Full Name

Dehydrogenase/Reductase 9

Function

3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone (PubMed:11294878, PubMed:29541409).

Plays also a role in the biosynthesis of retinoic acid from retinaldehyde (PubMed:11304534, PubMed:12618084).

Can utilize both NADH and NADPH.

Biological Process

9-cis-retinoic acid biosynthetic process Source: UniProtKB
Androgen metabolic process Source: UniProtKB
Epithelial cell differentiation Source: UniProtKB
Progesterone metabolic process Source: UniProtKB
Retinol metabolic process Source: UniProtKB

Cellular Location

Microsome membrane; Endoplasmic reticulum membrane. Associated with microsomal membranes.

View more

Anti-DHRS9 antibodies

+ Filters

Loading...

Mouse Anti-DHRS9 Recombinant Antibody (3C6) (CBMAB-A2217-LY)

Compare

Target: DHRS9

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3C6

Application*: WB, E

Human Recombinant DHRS9 protein, His Tag (V2LY-0526-LY3578)

Compare

Target: DHRS9

Expressed Host: E. coli

Sequence: Amino Acid: 18-319

Tag: His Tag

Mouse Anti-DHRS9 Recombinant Antibody (3C6) (V2LY-0425-LY285)

Compare

Target: DHRS9

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3C6

Application*: WB, E, IF

Mouse Anti-DHRS9 Recombinant Antibody (CBYCD-266) (V2LY-0425-LY284)

Compare

Target: DHRS9

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYCD-266

Application*: E, WB, IP

DHRS9 Matched Antibody Pair (340) (APMAB-340LY)

Compare

Target: DHRS9

Specificity: Human

Mouse Anti-DHRS9 Recombinant Antibody (CBYCD-266) (CBMAB-D0845-YC)

Compare

Target: DHRS9

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYCD-266

Application*: E, IC, IF, WB

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry