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FBLN2

This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Full Name
Fibulin 2
Research Area
Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).
Biological Process
Extracellular matrix organization Source: InterPro
Positive regulation of cell-substrate adhesion Source: GO_Central
Cellular Location
Extracellular matrix
PTM
O-glycosylated with core 1 or possibly core 8 glycans. It is unsure if the O-glycosylation is on Thr-347 or Ser-348.

Anti-FBLN2 antibodies

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Target: FBLN2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A2
Application*: SE, E
Target: FBLN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1D8
Application*: WB
Target: FBLN2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3582
Application*: E
Target: FBLN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1578
Application*: E, WB
Target: FBLN2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: EG1183
Application*: IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:40000
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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