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FGF16

This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion.

Full Name

Fibroblast Growth Factor 16

Research Area

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.

Biological Process

Animal organ morphogenesis Source: GO_Central
Cell-cell signaling Source: ProtInc
Cell differentiation Source: GO_Central
Fibroblast growth factor receptor signaling pathway Source: GO_Central
Positive regulation of brown fat cell proliferation Source: Ensembl
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of endothelial cell chemotaxis to fibroblast growth factor Source: UniProtKB
Positive regulation of gene expression Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Regulation of cell migration Source: GO_Central
Response to temperature stimulus Source: ProtInc
Signal transduction Source: ProtInc

Cellular Location

Secreted

Involvement in disease

Metacarpal 4-5 fusion (MF4):
A rare congenital malformation of the hand characterized by the partial or complete fusion of the fourth and fifth metacarpals. The anomaly occurs as an isolated trait or part of a syndrome.

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Anti-FGF16 antibodies

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Human, Cynomolgus Recombinant FGF16 protein (V2LY-0526-LY7701)

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Target: FGF16

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 1-207

Mouse Anti-FGF16 Recombinant Antibody (CBXF-1663) (V2LY-0925-LY1467)

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Target: FGF16

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: CBXF-1663

Application*: WB, P

Mouse Anti-FGF16 Recombinant Antibody (CBXF-2611) (V2LY-0925-LY1466)

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Target: FGF16

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXF-2611

Application*: WB

Mouse Anti-FGF16 Recombinant Antibody (CBXF-3339) (V2LY-0925-LY1465)

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Target: FGF16

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse, Rat, Cattle, Pig, Horse

Clone: CBXF-3339

Application*: WB, IP, IF, E

Mouse Anti-FGF16 Recombinant Antibody (CBXF-3337) (V2LY-0925-LY1464)

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Target: FGF16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat, Dog, Cattle, Pig, Chicken

Clone: CBXF-3337

Application*: WB, IP, IF, E, P

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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