FOSB
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
FOSB
Function
FosB interacts with Jun proteins enhancing their DNA binding activity.
Biological Process
Cellular response to calcium ion Source: Ensembl
Cellular response to hormone stimulus Source: Ensembl
Female pregnancy Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to cAMP Source: Ensembl
Response to corticosterone Source: Ensembl
Response to drug Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to morphine Source: Ensembl
Response to progesterone Source: Ensembl
Transcription by RNA polymerase II Source: Ensembl
Cellular response to hormone stimulus Source: Ensembl
Female pregnancy Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to cAMP Source: Ensembl
Response to corticosterone Source: Ensembl
Response to drug Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to morphine Source: Ensembl
Response to progesterone Source: Ensembl
Transcription by RNA polymerase II Source: Ensembl
Cellular Location
Nucleus
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Anti-FOSB antibodies
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Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-3593
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D8
Application*: IP, M
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1C9
Application*: IP, WB, M
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3124
Application*: WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXF-3123
Application*: F
Target: FOSB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1763
Application*: WB, IP, IF, P, E
Target: FOSB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1761
Application*: WB, IP, IF, E
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBXF-2656
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2350
Application*: IP
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2351
Application*: IP, WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-2249
Application*: CI, F, IF, P, IP, WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0819
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3679
Application*: WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-3739
Application*: WB, IP, P, IF, F, CI
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 83B1138
Application*: WB, F
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: CBYCD-473
Application*: WB, IP
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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