FOSB

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
FOSB
Function
FosB interacts with Jun proteins enhancing their DNA binding activity.
Biological Process
Cellular response to calcium ion Source: Ensembl
Cellular response to hormone stimulus Source: Ensembl
Female pregnancy Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to cAMP Source: Ensembl
Response to corticosterone Source: Ensembl
Response to drug Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to morphine Source: Ensembl
Response to progesterone Source: Ensembl
Transcription by RNA polymerase II Source: Ensembl
Cellular Location
Nucleus
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Anti-FOSB antibodies

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Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-3593
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D8
Application*: IP, M
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1C9
Application*: IP, WB, M
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3124
Application*: WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXF-3123
Application*: F
Target: FOSB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1763
Application*: WB, IP, IF, P, E
Target: FOSB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1761
Application*: WB, IP, IF, E
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBXF-2656
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2350
Application*: IP
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2351
Application*: IP, WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-2249
Application*: CI, F, IF, P, IP, WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0819
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3679
Application*: WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-3739
Application*: WB, IP, P, IF, F, CI
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 83B1138
Application*: WB, F
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: CBYCD-473
Application*: WB, IP
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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