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FTCD

FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.[supplied by OMIM
Full Name
formiminotransferase cyclodeaminase
Function
Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.

Binds and promotes bundling of vimentin filaments originating from the Golgi.
Biological Process
Cytoskeleton organization Source: Ensembl
Folic acid-containing compound metabolic process Source: ProtInc
Histidine catabolic process to glutamate and formamide Source: UniProtKB-UniPathway
Histidine catabolic process to glutamate and formate Source: UniProtKB-UniPathway
Tetrahydrofolate interconversion Source: UniProtKB-UniPathway
Cellular Location
Golgi apparatus; Centriole. More abundantly located around the mother centriole.
Involvement in disease
Glutamate formiminotransferase deficiency (FIGLU-URIA):
Autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.

Anti-FTCD antibodies

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Mouse Anti-FTCD Recombinant Antibody (CBLQ5-058) (CBMAB-2002CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBLQ5-058
Application*: IC, IF, IH, WB

Mouse Anti-FTCD Recombinant Antibody (CBXF-3561) (CBMAB-F2067-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3561
Application*: P, WB

Mouse Anti-FTCD Recombinant Antibody (CBXF-3592) (CBMAB-F2354-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3592
Application*: WB

Mouse Anti-FTCD Recombinant Antibody (CBXF-0942) (CBMAB-F2487-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBXF-0942
Application*: IF, IH, WB

Mouse Anti-FTCD Recombinant Antibody (CBXF-3215) (CBMAB-F3910-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3215
Application*: E, IF, IH, WB

Mouse Anti-FTCD Recombinant Antibody (1A7) (CBMAB-1852CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A7
Application*: P, WB

Mouse Anti-FTCD Recombinant Antibody (2B12) (CBMAB-1864CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B12
Application*: WB

Mouse Anti-FTCD Recombinant Antibody (3A4) (CBMAB-1875CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3A4
Application*: E, IF, P, WB

Mouse Anti-FTCD Recombinant Antibody (4A7) (CBMAB-1900CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4A7
Application*: P, WB

Mouse Anti-FTCD Recombinant Antibody (575) (CBMAB-1916CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: 575
Application*: WB, P

Mouse Anti-FTCD Recombinant Antibody (58K-9) (CBMAB-1917CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Pig, Rat, Hamster, Cattle
Clone: 58K-9
Application*: EM, IF, IH, P, WB

Mouse Anti-FTCD Recombinant Antibody (7C5) (CBMAB-1927CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7C5
Application*: WB, F

Mouse Anti-FTCD Recombinant Antibody (8C2) (CBMAB-1933CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8C2
Application*: P, WB

Mouse Anti-FTCD Recombinant Antibody (8F12) (CBMAB-1934CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8F12
Application*: WB

Mouse Anti-FTCD Recombinant Antibody (UMAB122) (CBMAB-2148CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: UMAB122
Application*: P

Mouse Anti-FTCD Recombinant Antibody (UMAB123) (CBMAB-2149CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: UMAB123
Application*: P

Mouse Anti-FTCD (AA 440-542) Recombinant Antibody (CBXF-0941) (CBMAB-F0308-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-0941
Application*: E, IC, IH, WB

Mouse Anti-FTCD Recombinant Antibody (CBXF-1273) (CBMAB-F2951-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1273
Application*: IH

Mouse Anti-FTCD Recombinant Antibody (CBXF-1274) (CBMAB-F2952-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-1274
Application*: IH

Mouse Anti-FTCD Recombinant Antibody (CBXF-0940) (CBMAB-F3215-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0940
Application*: SE, E, WB, IF, P

Mouse Anti-FTCD Recombinant Antibody (CBXF-1803) (CBMAB-F3338-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1803
Application*: WB, IP, IF, E

Mouse Anti-FTCD Recombinant Antibody (CBXF-1804) (CBMAB-F3339-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human, Dog
Clone: CBXF-1804
Application*: WB, IP, IF, P, E

Mouse Anti-FTCD (AA 440-541) Recombinant Antibody (CBXF-3216) (CBMAB-F3911-CQ)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3216
Application*: E, WB

Mouse Anti-FTCD Recombinant Antibody (5F6) (CBMAB-A3201-LY)

Datasheet SDS
Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5F6
Application*: WB, E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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