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FTCD

FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.[supplied by OMIM
Full Name
formiminotransferase cyclodeaminase
Function
Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.

Binds and promotes bundling of vimentin filaments originating from the Golgi.
Biological Process
Cytoskeleton organization Source: Ensembl
Folic acid-containing compound metabolic process Source: ProtInc
Histidine catabolic process to glutamate and formamide Source: UniProtKB-UniPathway
Histidine catabolic process to glutamate and formate Source: UniProtKB-UniPathway
Tetrahydrofolate interconversion Source: UniProtKB-UniPathway
Cellular Location
Golgi apparatus; Centriole. More abundantly located around the mother centriole.
Involvement in disease
Glutamate formiminotransferase deficiency (FIGLU-URIA):
Autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.
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Anti-FTCD antibodies

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Mouse Anti-FTCD Recombinant Antibody (5F6) (CBMAB-A3201-LY)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5F6
Application*: WB, E
Datasheet SDS

Mouse Anti-FTCD (AA 440-541) Recombinant Antibody (CBXF-3216) (CBMAB-F3911-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3216
Application*: E, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-3215) (CBMAB-F3910-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3215
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-1804) (CBMAB-F3339-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human, Dog
Clone: CBXF-1804
Application*: WB, IP, IF, P, E
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-1803) (CBMAB-F3338-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1803
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-0940) (CBMAB-F3215-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0940
Application*: SE, E, WB, IF, P
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-1274) (CBMAB-F2952-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-1274
Application*: IH
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-1273) (CBMAB-F2951-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1273
Application*: IH
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-0942) (CBMAB-F2487-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBXF-0942
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-3592) (CBMAB-F2354-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3592
Application*: WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBXF-3561) (CBMAB-F2067-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3561
Application*: P, WB
Datasheet SDS

Mouse Anti-FTCD (AA 440-542) Recombinant Antibody (CBXF-0941) (CBMAB-F0308-CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-0941
Application*: E, IC, IH, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (UMAB123) (CBMAB-2149CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: UMAB123
Application*: P
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (UMAB122) (CBMAB-2148CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: UMAB122
Application*: P
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (CBLQ5-058) (CBMAB-2002CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBLQ5-058
Application*: IC, IF, IH, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (8F12) (CBMAB-1934CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8F12
Application*: WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (8C2) (CBMAB-1933CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8C2
Application*: P, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (7C5) (CBMAB-1927CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7C5
Application*: WB, F
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (58K-9) (CBMAB-1917CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Pig, Rat, Hamster, Cattle
Clone: 58K-9
Application*: EM, IF, IH, P, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (575) (CBMAB-1916CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: 575
Application*: WB, P
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (4A7) (CBMAB-1900CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4A7
Application*: P, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (3A4) (CBMAB-1875CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3A4
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (2B12) (CBMAB-1864CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B12
Application*: WB
Datasheet SDS

Mouse Anti-FTCD Recombinant Antibody (1A7) (CBMAB-1852CQ)

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Target: FTCD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A7
Application*: P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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