FUT4
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
Full Name
Fucosyltransferase 4
Alternative Names
Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; Alpha (1,3) Fucosyltransferase, Myeloid-Specific; ELAM-1 Ligand Fucosyltransferase; ELAM Ligand Fucosyltransferase; Fucosyltransferase IV; FUC-TIV; FucT-IV; FCT3A; ELFT; Stage-Specific Embryonic Antigen 1;
Function
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Biological Process
Carbohydrate metabolic process Source: ProtInc
Fucosylation Source: GO_Central
L-fucose catabolic process Source: UniProtKB
Oligosaccharide biosynthetic process Source: Reactome
Oligosaccharide metabolic process Source: UniProtKB
Positive regulation of leukocyte tethering or rolling Source: UniProtKB
Protein glycosylation Source: UniProtKB
Regulation of leukocyte cell-cell adhesion Source: UniProtKB
Fucosylation Source: GO_Central
L-fucose catabolic process Source: UniProtKB
Oligosaccharide biosynthetic process Source: Reactome
Oligosaccharide metabolic process Source: UniProtKB
Positive regulation of leukocyte tethering or rolling Source: UniProtKB
Protein glycosylation Source: UniProtKB
Regulation of leukocyte cell-cell adhesion Source: UniProtKB
Cellular Location
Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi.
Topology
Cytoplasmic: 1-147
Helical: 148-172
Lumenal: 173-530
Helical: 148-172
Lumenal: 173-530
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Anti-FUT4 antibodies
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CompareTarget: FUT4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 6B11B4
Application*: E, WB, P, IF, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: Q89
Application*: IHC: 1:100
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: A135
Application*: FC, IHC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP800
Application*: ELISA, IHC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: Leu-M1
Application*: FC, IF, IHC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 6B2
Application*: IF, IHC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB476A
Application*: ELISA, IHC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB222
Application*: IF, FC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CB221
Application*: IF, FC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CB220
Application*: IF, FC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB219
Application*: IF, FC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CB218
Application*: IF, FC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: 8B2
Application*: WB, E
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G1-E10
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: P12
Application*: IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: TB98
Application*: IF/IC, C
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: W6D3
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: HI98
Application*: E, WB
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 7H143
Application*: FC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJC-3718
Application*: P
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJC-3717
Application*: F, IF, P
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBWJC-3716
Application*: F, IF
Target: FUT4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3715
Application*: P
Target: FUT4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3714
Application*: IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3713
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJC-3711
Application*: IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJC-3709
Application*: P, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJC-3708
Application*: IC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJC-2169
Application*: F, MC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBWJC-2168
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBWJC-2167
Application*: WB, F, IH, IC, IP, MC
Target: FUT4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP159
Application*: F, P
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: MMA
Application*: F, P
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: BRA4F1
Application*: E, F, C, P
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBXS-4307
Application*: F, C, IP
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5683
Application*: IC, IF, IH
Target: FUT4
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBXS-5658
Application*: WB, IP, IF, P, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: AHN1.1
Application*: F, FN, P
Target: FUT4
Host: Human
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXS-3559
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Mouse, Rat
Clone: MC480
Application*: WB, F, IH, IF, P, C
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXC-0651
Application*: F, C, P
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBXC-1367
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: MEM-158
Application*: F, IP
Target: FUT4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: FUT4/1478R
Application*: F, P, IF
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: By87a
Application*: WB, F, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBXC-2539
Application*: F, IH, IP, MC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBYY-C3267
Application*: F, IH, IP
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBYY-C2511
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C2510
Application*: WB, E
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBYY-C2509
Application*: F, IF
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBYY-C2508
Application*: IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBYY-C2506
Application*: F, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBYY-C0375
Application*: F, IF, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBFYC-2710
Application*: WB, P, C, IC, IF
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBFYC-2709
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBFYC-0502
Application*: F, MC
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBFYC-0496
Application*: F, C, IC, IP
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBL-LY-001
Application*: WB, P, C, IC, IC/IF
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: 5F17
Application*: F, IF, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: 3G75
Application*: IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 3F74
Application*: F, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B114
Application*: E, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 29
Application*: F, MC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1654
Application*: E, WB
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: SPM490
Application*: IF, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: MCS-1
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Mouse
Clone: CBXF-2084
Application*: P, IF, F
Target: FUT4
Host: Rabbit
Antibody Isotype: IgG, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-2037
Application*: P, IF, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CDLA15-1
Application*: F, IF, P
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E10
Application*: IF, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Rat
Clone: FUT4/815
Application*: P, IF, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: BRA-4F1
Application*: P, IF, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 476CT26.8.4
Application*: E, WB
Target: FUT4
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: FR4A5
Application*: IF, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Chimpanzee, Human
Clone: HI98
Application*: IH, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBLNC-152
Application*: MC, F
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 25G5
Application*: E, IH
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT275
Application*: P, IF, IC, E
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT276
Application*: P, IF, IC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT3970
Application*: WB
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3080
Application*: IH, IC
Target: FUT4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2894
Application*: F
Target: FUT4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: EC103
Application*: P, IF
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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