GDI2

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Full Name
GDP Dissociation Inhibitor 2
Function
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Biological Process
Protein transport Source: InterPro
Signal transduction Source: UniProtKB
Small GTPase mediated signal transduction Source: InterPro
Vesicle-mediated transport Source: GO_Central
Cellular Location
Cytoplasm; Membrane
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Anti-GDI2 antibodies

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Mouse Anti-GDI2 Recombinant Antibody (CF180) (CBMAB-FT302LY)

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Target: GDI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF180
Application*: ELISA, WB, IF, IHC
Datasheet SDS

Mouse Anti-GDI2 Recombinant Antibody (CBLG1-847) (CBMAB-G2784-LY)

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Target: GDI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBLG1-847
Application*: E (IA), WB
Datasheet SDS

Mouse Anti-GDI2 Recombinant Antibody (673) (V2LY-1225-LY1034)

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Target: GDI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 673
Application*: WB, P, IF
Datasheet SDS

Mouse Anti-GDI2 Recombinant Antibody (CF180) (V2LY-1225-LY1033)

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Target: GDI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF180
Application*: WB, IH, IF, E
Datasheet SDS

Mouse Anti-GDI2 Recombinant Antibody (CBLG1-847) (V2LY-1225-LY1032)

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Target: GDI2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBLG1-847
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-GDI2 Recombinant Antibody (673) (CBMAB-AP2488LY)

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Target: GDI2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 673
Application*: ELISA, IF, IHC, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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