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GNPDA1

Glucosamine-6-phosphate deaminase (EC 3.5.99.6) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).[supplied by OMIM, Jan 2010]

Full Name

Glucosamine-6-Phosphate Deaminase 1

Function

Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity).

Biological Process

Carbohydrate metabolic process Source: UniProtKB-KW
Generation of precursor metabolites and energy Source: UniProtKB
Glucosamine catabolic process Source: UniProtKB
N-acetylglucosamine catabolic process Source: GO_Central
N-acetylneuraminate catabolic process Source: GO_Central
Single fertilization Source: ProtInc
UDP-N-acetylglucosamine biosynthetic process Source: GO_Central

Cellular Location

Cytoplasm

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Anti-GNPDA1 antibodies

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Mouse Anti-GNPDA1 Recombinant Antibody (CBLG1-159) (CBMAB-G0586-LY)

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Target: GNPDA1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBLG1-159

Application*: WB, IP

Human GNPDA1 ELISA Kit (V2LY-0626-LY4201)

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Target: GNPDA1

Sensitivity: 0.018 ng/mL

Detection Range: 0.05-15 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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