HMG20A
HMG20A (High Mobility Group 20A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and chromatin binding. An important paralog of this gene is HMG20B.
Full Name
high-mobility group 20A
Function
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity).
Biological Process
Chromatin organization Source: UniProtKB
Negative regulation of neuron differentiation Source: Ensembl
Negative regulation of protein sumoylation Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of gene expression Source: GO_Central
Regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of neuron differentiation Source: Ensembl
Negative regulation of protein sumoylation Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of gene expression Source: GO_Central
Regulation of transcription, DNA-templated Source: UniProtKB
Cellular Location
Nucleus
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Anti-HMG20A antibodies
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Target: HMG20A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-1497
Application*: WB
Target: HMG20A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-1495
Application*: E, WB
Target: HMG20A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-1494
Application*: P
Target: HMG20A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-1493
Application*: P
Target: HMG20A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-3157
Application*: DB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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