HMG20A

HMG20A (High Mobility Group 20A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and chromatin binding. An important paralog of this gene is HMG20B.

Full Name

high-mobility group 20A

Function

Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity).

Biological Process

Chromatin organization Source: UniProtKB
Negative regulation of neuron differentiation Source: Ensembl
Negative regulation of protein sumoylation Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of gene expression Source: GO_Central
Regulation of transcription, DNA-templated Source: UniProtKB

Cellular Location

Nucleus

Anti-HMG20A antibodies

Mouse Anti-HMG20A Recombinant Antibody (CBFYH-1497) (CBMAB-H2455-FY)

Datasheet

SDS

Target: HMG20A

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYH-1497

Application*: WB

Mouse Anti-HMG20A (AA 153-263) Recombinant Antibody (CBFYH-1495) (CBMAB-H2453-FY)

Datasheet

SDS

Target: HMG20A

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-1495

Application*: E, WB

Mouse Anti-HMG20A (AA 1-281) Recombinant Antibody (CBFYH-1494) (CBMAB-H2452-FY)

Datasheet

SDS

Target: HMG20A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-1494

Application*: P

Mouse Anti-HMG20A (AA 1-281) Recombinant Antibody (CBFYH-1493) (CBMAB-H2451-FY)

Datasheet

SDS

Target: HMG20A

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-1493

Application*: P

Mouse Anti-HMG20A Monoclonal Antibody (CBFYH-3157) (CBMAB-H2449-FY)

Datasheet

SDS

Target: HMG20A

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYH-3157

Application*: DB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)