IFNE

Full Name

interferon, epsilon

Function

Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections (By similarity).

Biological Process

Adaptive immune response Source: GO_Central
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to bacterium Source: UniProtKB
Defense response to virus Source: UniProtKB
Humoral immune response Source: GO_Central
Natural killer cell activation involved in immune response Source: GO_Central
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: GO_Central
Response to exogenous dsRNA Source: GO_Central
T cell activation involved in immune response Source: GO_Central

Cellular Location

Secreted